PEGylation of mRNA

With decades of expertise in the field of activation and functionalization of PEG, BOC Sciences has established a mature PEG-modified drug development platform, which can provide high-quality PEGylation technology services for your mRNA therapy research and development. Whether you need simple linear PEG or highly branched PEG, need several or multiple conjugation sites, or have specific synthesis requirements, our professional scientists and technical support team will do their best to escort your R&D project!

Introduction of mRNA PEGylation

PEGylation of mRNA

Messenger RNA (mRNA) is the template for protein synthesis. There are multiple advantages to using mRNA as gene therapy, including a low potential risk of insertional mutagenesis, and a relatively easy, efficient, and safe transfection process. In addition, the raw material synthesis and product quality of mRNA are easier to standardize and have high reproducibility. To fully exploit the therapeutic potential of mRNA, PEGylation strategies are required to protect biologically fragile mRNA from nuclease degradation and help cross various biological barriers for efficient therapeutic protein expression.

Solutions of mRNA PEGylation

We support two service models:

  • You provide the mRNA yourself, and we will take care of its PEGylation. Delivered with the final product is an exclusive certificate of analysis for further testing at your site.
  • Comprehensive PEGylation method development services. In addition to PEGylated mRNA delivered to you, extension and transfer of PEGylation methods are also available.

PEGylation of mRNA

Accelerate Your mRNA Therapeutic Development

To accelerate your mRNA therapeutics development, we are able to perform preclinical studies on synthetic PEGylated mRNA, including efficacy, safety, pharmacokinetics and pharmacodynamics (PK/PD), and toxicity testing of PEGylated mRNA. If needed, custom made assays as requested by the customer.

PEGylation of mRNA

Technical Advantages

  • Rich comprehensive resource of chemistry and biology
  • Ultra-fast PEGylation development speed
  • Reduced risk of PEGylation failure
  • Continuous supply of high-quality PEGylated mRNA products

PEGylation of mRNA

How to order?

  • Project consulting
  • Project analysis
  • Plan finalization
  • Plan execution
  • Project completion
  • Product delivery

With a dedicated and experienced customer support team, BOC Sciences can efficiently provide PEGylation of mRNA from early development to clinical to commercial stage. We have a proven track record in developing bioconjugates and all synthetic bioconjugate projects are completed with the full support of our bioanalytical laboratory.

Contact us today and start with a project consultation to find out how we can help you develop the PEGylated mRNA you need to help bring your product to market faster.

Why BOC Sciences?

  • Large Stock

    More than 2000+ products in inventory

  • Global Delivery

    Warehouses in multiple cities to ensure fast delivery

  • mg to kg

    Multi specification for academic research and industrial production

  • 24/7 Technical Support

    Strict process parameter control to ensure product quality



Our Feature

BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.

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