Nitrophenyl carbonate (NPC) PEG
Protein Modification, Coupling
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With decades of expertise in the field of activation and functionalization of PEG, BOC Sciences has established a mature PEG-modified drug development platform, which can provide high-quality PEGylation technology services for your mRNA therapy research and development. Whether you need simple linear PEG or highly branched PEG, need several or multiple conjugation sites, or have specific synthesis requirements, our professional scientists and technical support team will do their best to escort your R&D project!

Messenger RNA (mRNA) is the template for protein synthesis. There are multiple advantages to using mRNA as gene therapy, including a low potential risk of insertional mutagenesis, and a relatively easy, efficient, and safe transfection process. In addition, the raw material synthesis and product quality of mRNA are easier to standardize and have high reproducibility. To fully exploit the therapeutic potential of mRNA, PEGylation strategies are required to protect biologically fragile mRNA from nuclease degradation and help cross various biological barriers for efficient therapeutic protein expression.
We support two service models:

To accelerate your mRNA therapeutics development, we are able to perform preclinical studies on synthetic PEGylated mRNA, including efficacy, safety, pharmacokinetics and pharmacodynamics (PK/PD), and toxicity testing of PEGylated mRNA. If needed, custom made assays as requested by the customer.


With a dedicated and experienced customer support team, BOC Sciences can efficiently provide PEGylation of mRNA from early development to clinical to commercial stage. We have a proven track record in developing bioconjugates and all synthetic bioconjugate projects are completed with the full support of our bioanalytical laboratory.
Contact us today and start with a project consultation to find out how we can help you develop the PEGylated mRNA you need to help bring your product to market faster.
Planning to purchase or looking for custom solutions?
Get in touch with our experts today! We'll respond within 24 hours to discuss your project needs and provide a customized quote.
From custom PEG synthesis to PEGylation support, explore tailored services designed to meet the specific needs of your research.
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