PEGylation of mRNA
With decades of expertise in the field of activation and functionalization of PEG, BOC Sciences has established a mature PEG-modified drug development platform, which can provide high-quality PEGylation technology services for your mRNA therapy research and development. Whether you need simple linear PEG or highly branched PEG, need several or multiple conjugation sites, or have specific synthesis requirements, our professional scientists and technical support team will do their best to escort your R&D project!
Introduction of mRNA PEGylation
Messenger RNA (mRNA) is the template for protein synthesis. There are multiple advantages to using mRNA as gene therapy, including a low potential risk of insertional mutagenesis, and a relatively easy, efficient, and safe transfection process. In addition, the raw material synthesis and product quality of mRNA are easier to standardize and have high reproducibility. To fully exploit the therapeutic potential of mRNA, PEGylation strategies are required to protect biologically fragile mRNA from nuclease degradation and help cross various biological barriers for efficient therapeutic protein expression.
Solutions of mRNA PEGylation
We support two service models:
- You provide the mRNA yourself, and we will take care of its PEGylation. Delivered with the final product is an exclusive certificate of analysis for further testing at your site.
- Comprehensive PEGylation method development services. In addition to PEGylated mRNA delivered to you, extension and transfer of PEGylation methods are also available.
Accelerate Your mRNA Therapeutic Development
To accelerate your mRNA therapeutics development, we are able to perform preclinical studies on synthetic PEGylated mRNA, including efficacy, safety, pharmacokinetics and pharmacodynamics (PK/PD), and toxicity testing of PEGylated mRNA. If needed, custom made assays as requested by the customer.
Technical Advantages
- Rich comprehensive resource of chemistry and biology
- Ultra-fast PEGylation development speed
- Reduced risk of PEGylation failure
- Continuous supply of high-quality PEGylated mRNA products
How to order?
- Project consulting
- Project analysis
- Plan finalization
- Plan execution
- Project completion
- Product delivery
With a dedicated and experienced customer support team, BOC Sciences can efficiently provide PEGylation of mRNA from early development to clinical to commercial stage. We have a proven track record in developing bioconjugates and all synthetic bioconjugate projects are completed with the full support of our bioanalytical laboratory.
Contact us today and start with a project consultation to find out how we can help you develop the PEGylated mRNA you need to help bring your product to market faster.
Why BOC Sciences?
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Large Stock
More than 2000+ products in inventory
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Global Delivery
Warehouses in multiple cities to ensure fast delivery
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mg to kg
Multi specification for academic research and industrial production
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24/7 Technical Support
Strict process parameter control to ensure product quality
Technical Support
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- Hydrophobic Interaction Chromatography (HIC) Technique
- PEGylated Protein Purification Techniques
- Radiolabeling Technique
- SDS-PAGE Technique
- Ultrafiltration Technique
Products
- Lipids
- PEG Derivatives by Structure
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PEG Derivatives by Functional Group
- Acrylate/Acrylamide/Methacrylate PEG
- Aldehyde (Ald/CHO)PEG
- Alkyne PEG
- Amino PEG, PEG amine(-NH2)
- Azide PEG, Azido PEG(-N3)
- Biotin PEG
- Boc/Fmoc protected amine PEG
- Carboxylic Acid(-COOH) PEG
- Cholesterol PEG
- DBCO PEG
- DSPE PEG
- Epoxide glycidyl ether PEG
- FITC PEG
- Halide (chloride, bromide) PEG
- Hydrazide PEG
- Hydroxyl(-OH) PEG
- Maleimide(-MAL) PEG
- Multi-Arm PEG
- NHS ester PEG
- Nitrophenyl carbonate (NPC) PEG
- Norbornene PEG
- Olefin/Alkene/Vinyl PEG
- Orthopyridyl disulfide (OPSS) PEG
- Phosphate PEG
- Rhodamine PEG
- SCM PEG
- Silane PEG
- Sulfonate (tosyl, mesyl, tresyl) PEG
- tert-Butyl protected carboxylate PEG
- Thiol(-SH) PEG
- Vinylsulfone PEG
- PEG Copolymers
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PEG Raw Materials
- Small-molecule Polyethylene Glycol
- Polyethylene Glycol 1000
- Polyethylene Glycol 10000
- Polyethylene Glycol 1500
- Polyethylene Glycol 200
- Polyethylene Glycol 2000
- Polyethylene Glycol 20000
- Polyethylene Glycol 400
- Polyethylene Glycol 4000
- Polyethylene Glycol 600
- Polyethylene Glycol 6000
- Polyethylene Glycol 800
- Polyethylene Glycol 8000
Services
- PEGylation Services
- PEGylation Analysis and Method Verification
- Surface Modification and Functionalization
- PEGylated Biodegradable Polymers Synthesis
- Monodisperse PEG Synthesis
- Custom Synthesis PEG Derivatives
- PEG cGMP Manufacture
- PEG Crosslinking Services
Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
- PEG for Cosmetic Application
- PEG for Drug Delivery
- PEG for Imaging Diagnosis
- PEG for Pharmaceutical Preparation
- PEG for Tissue Engineering
- PEGylated Protein Purification Techniques
- Radiolabeling Technique
- SDS-PAGE Technique
- Size Exclusion Chromatography (SEC) Technique
- Ultrafiltration Technique
- Industry News
Our Feature
BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.

PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS

PEG linkers For Drug
Improved Circulation Half-Life
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