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Alkyne-PEG-MAL

Cat. No. Product Name CAS No.
BPG-2831 Alkyne-PEG-MAL, MW 3.5k Inquiry

Synonyms: Alkyne-PEG-Maleimide

Alkyne-PEG-MAL is a kind of heterobifunctional PEG reagent with alkyne and maleimide groups at both ends of the molecular chain. It can enable the connection of an azide containing compound or biomolecule to one with a thiol. The terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The maleimide group is selective for the mercaptan group on the cysteine side chain. Hydrophilic PEG spacers increase the water solubility of the reagent and allow easy modification of cysteine-containing biomolecules, such as antibodies, proteins, and peptides with terminal alkynes. PEG spacers also reduce the aggregation of modified proteins stored in solution by increasing hydrophilicity.

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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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APPLICATIONS

APPLICATIONS

PEG linkers For Drug

Improved Circulation Half-Life

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