Sulfonate (tosyl, mesyl, tresyl) PEG
Activation, Leaving Groups
| Catalog No. | Name | Structure | M.W. | Purity | Buy |
|---|---|---|---|---|---|
| BPG-2831 | Alkyne-PEG-MAL, MW 3.5k |
|
N/A | N/A | |
| BPG-2696 | Y-shape-PEG-Alkyne, MW 40k |
|
N/A | N/A | |
| BPG-1108 | 8-Arm PEG-Alkyne, MW 10k-40k |
|
Customizable | N/A | |
| BPG-0989 | 4-Arm PEG-Alkyne, MW 2k-20k |
|
Customizable | N/A | |
| BPG-0431 | Alkyne-PEG-Alkyne, MW 600-20k |
|
Customizable | N/A | |
| BPG-0034 | mPEG-Alkyne, MW 550-40k |
|
Customizable | N/A |
Background
A polymer with both alkyne and PEG functional groups is referred to as alkyne PEG. Alkyne functional groups added to PEG allow for specialized chemical processes like click chemistry. Click chemistry is an efficient and selective reaction capable of attaching various molecules to PEG, thereby facilitating the development of PEG-based functionalized materials. Alkyne PEGs are important tools in the domains of materials science and medicinal research because of their adaptability and simplicity in chemical modification.
Click chemistry reactions, notably those involving azide-alkyne cycloadditions (CuAAC) that are catalyzed by copper, can further functionalize the insertion of alkyne groups into PEG. Alkyne-functionalized PEG can interact with biomolecules or molecules with azide functionalities to create covalent bonds and novel functionalized PEG conjugates. This bioorthogonal, highly selective, and click chemical process may be carried out in the presence of living systems without impairing their regular operation. Alkyne-functionalized PEG is therefore a desirable technique for the creation of bioconjugates and specific drug delivery systems.

Alkyne PEGs can be employed for surface modification, cross-linking, and other chemical alterations outside click chemistry processes. A flexible framework for further functionalization and personalization of PEG-based materials is offered by the alkyne group. Bioconjugation, drug delivery, tissue engineering, diagnostics, and imaging are a few popular uses for alkyne PEGs.
The 4-arm PEG alkyne refers to a molecule consisting of a PEG backbone with four arms or branches and an alkyne functional group attached to each branch. The 4-arm structure of the PEG molecule provides multiple attachment sites, allowing simultaneous conjugation of multiple molecules, thereby increasing the potential for complex biomolecular modification or various structural assembly. This makes 4-Arm PEG Alkyne an invaluable tool in biomedical research and applications where precise control of molecular structure, biocompatibility, and conjugation versatility are required.
Alkynes PEG (polyethylene glycol) can be classified according to their molecular weight and functional groups.
- Low molecular weight alkyne PEG: Typically refers to PEGs with a molecular weight below 10,000 Da.
- Medium molecular weight alkyne PEG: Refers to PEG with a molecular weight between 10,000 and 100,000 Da.
- High molecular weight alkyne PEG: Refers to PEG with a molecular weight above 100,000 Da.
- Monofunctional Alkyne PEG: Contains a single alkyne functional group and can be used for various chemical modifications or conjugations.
- Bifunctional alkyne PEG: Contains two alkyne functional groups, allowing cross-linking or multiple conjugation sites, such as Alkyne PEG Alkyne.
- Multifunctional alkyne PEG: Contains more than two alkyne functional groups, enabling complex cross-linking or conjugation strategies.
In terms of PEG Alkyne supply, BOC Sciences offers a variety of PEG Alkyne products with different molecular weights and functional groups. We ensure the high purity and quality of our PEG products for research, development and industrial applications. Our production facilities are equipped with state-of-the-art equipment and run by an experienced team of chemists and engineers. Our comprehensive understanding of PEG chemistry enables precise control of molecular weight, functionality and purity in PEG cGMP manufacturing. The manufacturing process is closely monitored and undergoes strict quality control procedures to guarantee the consistency and reliability of the final product.
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