PEG Copolymers

PEG Copolymers

• Dendrimer PEG Copolymer
• PEG-PCL Polycaprolactone
• PEG-PGA Polyglutamic Acid
• PEG-PLA Polylactic acid
• PEG-PLGA Copolymer
• PEG-Plys Polylysine
• PEGylated Hyaluronic Acid (HA)
• PEGylated RGD Peptide
• Others

Polyethylene glycol (PEG) has ubiquitous use in biomaterials, due to its good biocompatibility, non-toxicity and low immunogenicity. With the rapid development of diblock copolymers in biomedicine, nanomaterials, sustained release and photonic crystals fields, there are more and more studies on the use of PEG as basic skeleton to develop copolymers. PEGylated copolymers mainly include carbohydrates, hyaluronic acid, polyamino acid and others. PEGylated copolymers have been developed for a wide range of applications. In the biomedical field, the applications mainly focus on drug delivery, drug release, drug solubility enhancement, microencapsulation, implants, tissue scaffolding and others. Biodegradable polyesters, including those made of caprolactones, have been approved for clinical use.

Figure 1. PEG-dendritic block copolymers for biomedical applications (Sousa-Herves, A., et al., 2012)

BOC Sciences provides various high quality diblock (A-B), triblock (A-B-A) and pentablock (A-B-C-B-A) copolymers of PEG with dendrimer, poly(caprolactone) (PCL), poly(L-lactide) whihc also called poly(L-lactic acid) (PLLA), poly(D-Lactide) (PDLA), poly(D,L-lactide) (PDLLA), poly(lactide-co-caprolactone) (PLCL), poly(lactide-co-glycolide) (PLGA), poly(trimethylene carbonate) (PTMC), poly(delta-valerolactone) (PVL), polyethyleneimine (PEI), polylysine (Plys), hyaluronic acid (HA), RGD peptides and polyglutamic acid (PGA). PEG copolymers provided by BOC Sciences have the following characteristics:

• High quality
• High purity
• Stable structure
• High reactivity
• Amphiphilicity
• Biodegradable
• Non-toxic

BOC Sciences also provides customized synthesis services for PEGylated copolymers with different molecular weights and other reactive functional groups to meet the specific needs of our customers. We aim to provide our customers with high quality PEG products and all-round services.

Please select the needed products according to our product lists. If you have any demand for the copolymers not listed and would like to know more details of our products and services, please feel free to contact us.

Reference

1. Sousa-Herves, A., et al., 2012. PEG-dendritic block copolymers for biomedical applications. New Journal of Chemostry, 36(2), pp. 205–210.