Methoxy Linear PEG (mPEG)

BOC Sciences is a leading supplier of mPEG compounds with a range of molecular weights and functional groups. Because of the high purity and quality of our mPEG products, they are guaranteed to meet the most exacting requirements of the pharmaceutical and biomedical industries. Global distribution capabilities of BOC Sciences allow prompt and effective shipping of mPEG products to clients all over the world.

What is Methoxy Linear PEG (mPEG)?

Methoxy linear PEG (mPEG) is a type of PEG that has methoxy (CH3O) groups attached to its linear chain. It includes monofunctional or heterobifunctional mPEG derivatives with various functional groups, such as Amine (NH2), Thiol (SH), Azide (N3), NHS ester, Maleimide (Mal), Carboxylic acid (COOH), Alkyne, Silane, Biotin, DBCO, DSPE, etc. mPEG is a water-soluble and biocompatible high-molecular polymer. It is frequently employed in the domains of medical research, drug release, nanotechnology, cell culture, and new materials because of its special qualities, including low toxicity, non-immunogenicity, and high solubility.

Structural Features of mPEG

Methoxy (CH3O) groups are joined to the end of a linear chain of repeating ethylene glycol units to form the structure of mPEG. mPEG's general formula is HO(CH2CH2O)nCH2CH2OCH3, where n is the number of ethylene glycol units in the chain and varies based on the polymer's molecular weight. The methoxy groups attached to the end of the PEG chain provide steric hindrance and reduce protein adsorption, making it a useful polymer for various biomedical and pharmaceutical applications.

Schematic structure of linear PEG, methoxy linear PEG (mPEG), and branched monomethoxy-PEGFig. 1. Schematic structure of linear PEG, methoxy linear PEG (mPEG), and branched monomethoxy-PEG (mPEG2).

Application Fields of mPEG

The molecular weights of mPEG, which range from a few hundred to several thousand Daltons, can be adjusted to satisfy the demands of various applications. It is frequently employed as a surface modification to lessen the immunogenicity and toxicity of pharmaceuticals as well as to increase their stability, solubility, and bioavailability. In the research on ligands, polypeptide synthesis support, graft polymer compounds, novel materials, functional coatings modified with polyethylene glycol, and other facets of the active compound are examined. In order to avoid biofouling and increase the biocompatibility of medical equipment like implants and catheters, mPEG is also applied as a coating. In order to promote cell adhesion and proliferation, it is also utilized in tissue engineering and regenerative medicine.

Highlights of Our mPEG Products

Because of its numerous benefits, the chemistry of mPEG makes it a valuable and popular polymer for usage in numerous biological and pharmaceutical applications. For instance, mPEG is a perfect polymer for use in a variety of biomedical applications like medication delivery and tissue engineering since it is biocompatible and non-toxic. In addition, mPEG is highly water-soluble, which makes it easy to handle and formulate into different drug delivery systems such as micelles, liposomes, and nanoparticles. Our mPEG product features include:

Methoxy Linear PEG (mPEG)

  • Biocompatibility
  • Water solubility
  • Low immunogenicity
  • Resistance to protein adsorption
  • Tailored molecular weights
  • Chemical versatility

If you are interested in our PEG products and PEGylation services, please contact us now for more information.

Why BOC Sciences?

  • Large Stock

    More than 2000+ products in inventory

  • Global Delivery

    Warehouses in multiple cities to ensure fast delivery

  • mg to kg

    Multi specification for academic research and industrial production

  • 24/7 Technical Support

    Strict process parameter control to ensure product quality



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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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