Polyethylene Glycol 400

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Category	Polyethylene Glycol 400
Catalog NO.	BPG-1627
Product Name	Polyethylene Glycol 400
Molecular Formula	C20H40O3
Molecular Weight	380-420

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Custom Synthesis
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Product Information
Application
References
Documents
Reviews

Product Information

Description	Polyethylene Glycol 400 is a multi-faceted compound extensively exploited in the realm of biomedicine and harbors outstanding solubility and negligible toxicity. It stands as the go-to carrier within pharmaceutical dispensation mechanisms, whether for oral or topical drug development. It has a wide range of uses as an effective pharmaceutical ingredient for treating dry eyes, relieving constipation, and as an ingredient in softening ointments and emollients.
Synonyms	PEG 400
IUPAC Name	2-hydroxyethyl octadecanoate
Canonical SMILES	CCCCCCCCCCCCCCCCCC(=O)OCCO
InChI	InChI=1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3
InChIKey	RFVNOJDQRGSOEL-UHFFFAOYSA-N
Melting Point	30-34 °C
Flash Point	MYRJ 45: 500 °F OC
Solubility	POLYETHYLENE GLYCOL ESTERS AND ETHERS INCR THE WATER SOLUBILITY OF TYROTHRICIN .
Appearance	Clear, colorless liquid
Storage	Store at room temperature.
Pictogram(s)	Irritant
Signal	Warning
Precautionary Statement Codes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

References

1. Mai Y, Dou L, Murdan S, et al. An animal's sex influences the effects of the excipient PEG 400 on the intestinal P-gp protein and mRNA levels, which has implications for oral drug absorption.European journal of pharmaceutical sciences, 2018, 120: 53-60.
2. Mai Y, Murdan S, Awadi M, et al. Establishing an in vitro permeation model to predict the in vivo sex-related influence of PEG 400 on oral drug absorption. International journal of pharmaceutics, 2018, 542(1-2), 280-287.

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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.