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DOTMA

CAS No. CAS No.: 104162-48-3
Cat No. Cat No.: BPG-3619
Purity Purity: 98%
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DOTMA is one of the first cationic lipid used for gene transfection. It is an effective transfection agent in vitro and in vivo. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome.

Category Cationic Lipid
Molecular Formula C42H84ClNO2
Molecular Weight 670.59
Shipping Ambient temperature
Storage Store at -20 °C
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DOTMA

Structure of 104162-48-3

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BPG-3619 DOTMA In stock

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  • Specification
Synonyms 1-Propanaminium, N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecen-1-yloxy]-, chloride(1:1); 1-Propanaminium, N,N,N-trimethyl-2,3-bis(9-octadecenyloxy)-, chloride, (Z,Z)-; 1-Propanaminium, N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenyloxy]-, chloride; N-(2,3-Di(9-(Z)-octadecenyloxy))prop-1-yl-N,N,N-trimethylammonium chloride; N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium chloride; Trimethyl[2,3-(dioleyloxy)propyl]ammonium chloride
IUPACName 2,3-bis[(Z)-octadec-9-enoxy]propyl-trimethylazanium;chloride
CanonicalSMILES CCCCCCCCC=CCCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCCC=CCCCCCCCC.[Cl-]
InChI InChI=1S/C42H84NO2.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-44-41-42(40-43(3,4)5)45-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,42H,6-19,24-41H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
InChIKey LDGWQMRUWMSZIU-LQDDAWAPSA-M
MeltingPoint 16.8 °C
Purity 98%
RelatedCAS 122342-03-4 (free base) 104872-42-6 (rac-isomer)

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