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Category Cationic Lipid
Catalog NO. BPG-3619
Product Name DOTMA
CAS 104162-48-3
Molecular Formula C42H84ClNO2
Molecular Weight 670.6
DOTMA
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Description DOTMA is one of the first cationic lipid used for gene transfection. It is an effective transfection agent in vitro and in vivo. DOTMA carries a positive charge on the surface of liposomes which condenses anionic nucleic acids and promotes efficient interactions between the cell membrane and the liposome.
Synonyms DOTMA; 104162-48-3; Trimethyl[2,3-(dioleyloxy)propyl]ammonium Chloride; N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium; 104872-42-6; 2,3-bis[(Z)-octadec-9-enoxy]propyl-trimethylazanium;chloride; N-[1-(2,3-Dioleyloxy)propyl]-N,N,N-trimethylammonium Chloride; N,N,N-Trimethyl-2,3-bis((Z)-octadec-9-en-1-yloxy)propan-1-aminium chloride
IUPAC Name 2,3-bis[(Z)-octadec-9-enoxy]propyl-trimethylazanium;chloride
Canonical SMILES CCCCCCCCC=CCCCCCCCCOCC(C[N+](C)(C)C)OCCCCCCCCC=CCCCCCCCC.[Cl-]
InChI InChI=1S/C42H84NO2.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-44-41-42(40-43(3,4)5)45-39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,42H,6-19,24-41H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
InChIKey LDGWQMRUWMSZIU-LQDDAWAPSA-M
Purity 0.98
Storage -20°C

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