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2-(2-(2-Aminoethoxy)ethoxy)acetic acid

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Category	Small-molecule Heterobifunctional PEG
Catalog NO.	BPG-1712
Product Name	2-(2-(2-Aminoethoxy)ethoxy)acetic acid
CAS	134978-97-5
Molecular Formula	C6H13NO4
Molecular Weight	163.17

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Catalog Number	Size	Price	Stock	Quantity
BPG-1712	1 g	$176	In stock

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Description	H2N-PEG2-CH2COOH belongs to a polyethylene glycol (PEG) linker covalently bound to E3 Ligase binding group (E3LB) and protein binding group (PB). H2N-PEG2-CH2COOH is a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and PROTACs.
Synonyms	Amino-PEG2-CH2CO2H; Amino-PEG2-CH2COOH; Amino-PEG2-acetic acid
IUPAC Name	2-[2-(2-aminoethoxy)ethoxy]acetic acid
Canonical SMILES	C(COCCOCC(=O)O)N
InChI	InChI=1S/C6H13NO4/c7-1-2-10-3-4-11-5-6(8)9/h1-5,7H2,(H,8,9)
InChIKey	RUVRGYVESPRHSZ-UHFFFAOYSA-N
Boiling Point	323.8 °C at 760 mmHg
Purity	≥95%
Density	1.177 g/cm³
Solubility	Soluble in DMSO (10 mm)
Appearance	White Powder
Storage	Store at 2-8°C
Exact Mass	163.08445790
LogP	-0.23680
Pictogram(s)	Irritant
Signal	Warning
Precautionary Statement Codes	P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501

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