DOPE

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Category	Phospholipid
Catalog NO.	BPG-3885
Product Name	DOPE
CAS	4004-05-1
Molecular Formula	C41H78NO8P
Molecular Weight	744.1

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Product Information

Description	DOPE, also known as 1,2-Dioleoyl-sn-glycero-3-PE or 1,2-DOPE, is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
Synonyms	18:1 PE; 1,2-Dioleoyl-sn-glycero-3-PE; 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine; 1,2-DOPE
IUPAC Name	[(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] (Z)-octadec-9-enoate
Canonical SMILES	CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCCC=CCCCCCCCC
InChI	InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1
InChIKey	MWRBNPKJOOWZPW-NYVOMTAGSA-N
Boiling Point	759.22°C at 760 mmHg
Melting Point	200 °C
Purity	0.95
Density	1.008±0.06 g/cm3 (Predicted)
Solubility	Chloroform: 3.3 mg/ml
Appearance	Freeze-dried Powder
Shelf Life	≥ 2 years
Storage	-20°C

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