Multi-Arm PEG
Polyethylene glycol (PEG) is a versatile polymer that has found numerous applications in various fields, including drug delivery, biotechnology, and materials science. One of the most promising forms of PEG is multi-arm PEG, which is a branched polymer with multiple arms. Multi-arm PEG is an excellent candidate for various applications due to its unique characteristics, such as high water solubility, biocompatibility, and low toxicity. BOC Sciences is a leading supplier of multi-armed PEG and other PEG derivatives. We offer a wide range of multi-armed PEG products with different molecular weights, arm lengths and functional groups. Our multi-arm-PEG products include a variety of functionalized and structured 2-Arm PEGs, 3-Arm PEGs, 4-Arm PEGs, 6-Arm PEGs and 8-Arm PEGs.
Fig. 1. Examples of applications of 4-arm PEG (Frontiers in Bioengineering and Biotechnology. 2019, 7: 410).
Applications of Multi-Arm PEG
Multi-armed PEGs have been widely used in various fields such as drug delivery, tissue engineering, and diagnostic imaging.
Multi-arm PEG in Drug Delivery
Multi-arm PEGs are used to improve the pharmacokinetics and biodistribution of drugs. Multi-armed PEG can be used as a coating material for nanoparticles and liposomes to enhance drug stability and circulation time in the bloodstream. In addition, multi-arm PEG can also be used as a linker to couple drugs to antibodies or polypeptides to improve the specificity and efficacy of drugs.
Multi-arm PEG in Tissue Engineering
Multi-armed PEGs can be used to create hydrogels that mimic tissue extracellular matrix (ECM), which can be used as scaffolds for cell growth and tissue regeneration. In addition, the multi-arm PEG hydrogel can be used as a drug delivery vehicle for growth factors and cytokines, which can promote tissue regeneration and repair.
Multi-Arm PEG in Diagnostic Imaging
Multi-arm PEG can be used to create contrast agents for magnetic resonance imaging (MRI) and computed tomography (CT) scans. For example, multi-armed PEG can be used as a coating material for nanoparticles, which can enhance the contrast of images. In addition, multi-arm PEG can also be used as a linker to couple imaging agents to antibodies or peptides, thereby improving the specificity and sensitivity of imaging.
Features of Multi-Arm PEG
- Multi-arm PEG is highly water soluble which makes it easy to handle and process.
- Multi-arm PEGs are biocompatible and non-toxic, making them safe for use in biological systems.
- The high molecular weight nature of multi-arm PEG makes it less prone to degradation and increases its stability in the bloodstream.
- A multi-arm PEG has multiple arms, which increases its surface area and allows multiple sites for functionalization.
Custom Synthesis Services of Multi-Arm PEG
BOC Sciences also provides custom synthesis services for multi-armed PEGs and other PEG derivatives. We have a team of experienced chemists and state-of-the-art facilities to produce multi-armed PEGs of high purity and quality. BOC Sciences is committed to providing quality products and services to customers in the polyethylene glycol field.
Our PEG cGMP Manufacturing Advantages
BOC Sciences also provides low to high volume cGMP manufacturing of PEG. Our PEG cGMP manufacturing always ensures high purity and quality of the final product. Our cGMP manufacturing process strictly adheres to regulatory guidelines, which ensures that the final product meets all necessary safety and quality standards. We allow full traceability of products from raw material to finished product. Contact us to learn more about our products and services.
Reference
- Sheth, S. et al. Predicting Drug Release From Degradable Hydrogels Using Fluorescence Correlation Spectroscopy and Mathematical Modeling. Frontiers in Bioengineering and Biotechnology. 2019, 7: 410.
Why BOC Sciences?
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Large Stock
More than 2000+ products in inventory
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Global Delivery
Warehouses in multiple cities to ensure fast delivery
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mg to kg
Multi specification for academic research and industrial production
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24/7 Technical Support
Strict process parameter control to ensure product quality
Technical Support
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- Hydrophobic Interaction Chromatography (HIC) Technique
- PEGylated Protein Purification Techniques
- Radiolabeling Technique
- SDS-PAGE Technique
- Ultrafiltration Technique
Products
- Lipids
- PEG Derivatives by Structure
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PEG Derivatives by Functional Group
- Acrylate/Acrylamide/Methacrylate PEG
- Aldehyde (Ald/CHO)PEG
- Alkyne PEG
- Amino PEG, PEG amine(-NH2)
- Azide PEG, Azido PEG(-N3)
- Biotin PEG
- Boc/Fmoc protected amine PEG
- Carboxylic Acid(-COOH) PEG
- Cholesterol PEG
- DBCO PEG
- DNP PEG
- DSPE PEG
- Epoxide glycidyl ether PEG
- FITC PEG
- Folate PEG
- Halide (chloride, bromide) PEG
- Hydrazide PEG
- Hydroxyl(-OH) PEG
- Maleimide(-MAL) PEG
- NHS ester PEG
- Nitrophenyl carbonate (NPC) PEG
- Norbornene PEG
- Olefin/Alkene/Vinyl PEG
- Orthopyridyl disulfide (OPSS) PEG
- Phosphate PEG
- Rhodamine PEG
- SCM PEG
- Silane PEG
- SPDP PEG
- Sulfonate (tosyl, mesyl, tresyl) PEG
- tert-Butyl protected carboxylate PEG
- Thiol(-SH) PEG
- Vinylsulfone PEG
- PEG Copolymers
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PEG Raw Materials
- Small-molecule Polyethylene Glycol
- Polyethylene Glycol 1000
- Polyethylene Glycol 10000
- Polyethylene Glycol 1500
- Polyethylene Glycol 200
- Polyethylene Glycol 2000
- Polyethylene Glycol 20000
- Polyethylene Glycol 400
- Polyethylene Glycol 4000
- Polyethylene Glycol 600
- Polyethylene Glycol 6000
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- Polyethylene Glycol 8000
Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
- Ion Exchange Chromatography (IEX) Technique
- PEG for Chemical Synthesis
- PEG for Cosmetic Application
- PEG for Drug Delivery
- PEG for Imaging Diagnosis
- PEG for Pharmaceutical Preparation
- PEG for Tissue Engineering
- PEG Purification Techniques of Plasmid DNA
- PEGylated Protein Purification Techniques
- Polyethylene Glycol (PEG) Modifier Selection Guide
- Radiolabeling Technique
- SDS-PAGE Technique
- Size Exclusion Chromatography (SEC) Technique
- Ultrafiltration Technique
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
Our Feature
BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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