Acyl CoA - Unsaturated Fatty Acid

Unsaturated fatty acids acyl coenzyme A (Acyl CoA) is the esterification product of Acyl CoA with unsaturated fatty acids. When unsaturated fatty acids enter the cell, they are converted to the corresponding form of Acyl CoA, a process that involves the catalytic action of acyl coenzyme A synthetase. Once unsaturated fatty acids are converted to the acyl coenzyme A form, they can enter the fatty acid beta-oxidation pathway and be metabolized by a series of enzymes. BOC Sciences offers a variety of products related to CoA and its derivatives, more than a dozen of which are currently available in the form of acyl-CoA (unsaturated fatty acids), which includes the following 13 :0 Coenzyme A ammonium salt, 14:0 Coenzyme A (ammonium salt), 23:0 Coenzyme A (ammonium salt) and so on. Our products are constantly being updated and we can customize products in addition to those listed.

Examples of Acyl CoA

Acyl CoA-Oleic Acid

Oleic acid is a monounsaturated fatty acid commonly found in vegetable and animal fats and oils. It is an 18-carbon long fatty acid with a double bond located between the 9th and 10th carbon atoms of the carbon chain. The formation and metabolism of acyl CoA-oleic acid is essential for the regulation of intracellular energy homeostasis, lipid metabolism and cellular function.

Acyl CoA-Linoleic Acid

Linoleic acid is an omega-6 polyunsaturated fatty acid found primarily in vegetable oils such as sunflower, soybean and corn oils. Linoleic acid is an essential fatty acid, which means that the body cannot synthesize it on its own and must obtain it through the diet. The conversion of linoleic acid to acyl CoA-linoleic acid is an important step in the intracellular utilization of linoleic acid for energy production and the synthesis of bioactive substances.

Acyl CoA-Alpha-linolenic Acid

Alpha-linolenic acid is an omega-3 polyunsaturated fatty acid. Acyl CoA-alpha-linolenic acid is involved in a variety of metabolic pathways and biological processes within the cell. It is a metabolic intermediate in the metabolism of omega-3 fatty acids and can be used to synthesize other important lipid molecules such as phospholipids and triglycerides. In addition, alpha-linolenic acid is a precursor substance for the metabolic pathway synthesis of other bioactive substances such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid).

How is Acyl CoA-Unsaturated Fatty Acid Prepared?

Step 1: First, fatty acid extraction is performed. Saturated fatty acids can be extracted from natural sources such as vegetable oils or animal fats by solvent extraction, fatty acid esterification or acid hydrolysis.

Step 2: Then, chemical or biocatalytic reactions can be used to convert saturated fatty acids to unsaturated fatty acids.

Step 3: Finally, the unsaturated fatty acids are combined with coenzyme A (CoA) to form unsaturated fatty acyl coenzyme A. This step can be accomplished by an enzyme-catalyzed reaction that combines unsaturated fatty acids with ATP (adenosine triphosphate) and coenzyme A under appropriate conditions.

Applications of Acyl CoA-Unsaturated Fatty Acid

Pharmaceuticals and nutritional supplements. Acyl CoA can be used as an ingredient in drugs and nutritional supplements. For example, some of the omega-3 family of unsaturated fatty acids (e.g., EPA and DHA) are used in the prevention and treatment of heart disease, as well as brain health support agents.

Food industry. Acyl CoA can be used for processing and modification in the food industry. They can be added as functional food ingredients to a variety of products such as cookies, breads, cereals, juices and more.

Biofuel production. Acyl CoA can be useful in biofuel production, which is considered a sustainable and environmentally friendly way of producing energy.

BOC Sciences specializes in the research, development, production and marketing of coenzyme A and derivatives. If you are interested in our products, please feel free to contact us.