| Category | Small-molecule Heterobifunctional PEG |
| Molecular Formula | C6H14ClNO4 |
| Molecular Weight | 199.63 |
| Storage | Store at 2-8 °C |
2-(2-(2-Aminoethoxy)ethoxy)acetic acid hydrochloride
2-(2-(2-aminoethoxy)ethoxy)acetic acid hydrochloride is a heterobifunctional PEG linker containing an amino group and a carboxylic acid. The amino group can react with carboxylic acids, activated NHS esters, carbonyls and so on, and the carboxylic acid can be reacted with amino groups in the presence of activators.
Structure of 134979-01-4
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | [2-(2-Aminoethoxy)ethoxy]acetic acid hydrochloride; 8-Amino-3,6-dioxaoctanoic acid hydrochloride; O2Oc.HCl; Ado.HCl; Adoa.HCl; H-AEEA.HCl; Acetic acid, 2-[2-(2-aminoethoxy)ethoxy]-, hydrochloride (1:1); AEEA-OH HCl; CH2COOH-PEG2-NH2.HCl; H-Ado-OH.HCl; AEEA.HCl; H-O2Oc-OH HCl; Ado-OH HCl |
| IUPACName | 2-[2-(2-aminoethoxy)ethoxy]acetic acid;hydrochloride |
| CanonicalSMILES | C(COCCOCC(=O)O)N.Cl |
| InChI | InChI=1S/C6H13NO4.ClH/c7-1-2-10-3-4-11-5-6(8)9;/h1-5,7H2,(H,8,9);1H |
| InChIKey | NGPFHPADAGAUDR-UHFFFAOYSA-N |
| Purity | >99% |
| RelatedCAS | 134978-97-5 (free base) |
| PEGType | PEG / Oligoethylene Glycol Building Block |
| PEGArchitecture | Linear |
| Functionality | Monofunctional (Reactive) |
| ReactiveToward | Primary Amines (after activation) |
| ReactionChemistry | Carbodiimide-Mediated Amide Coupling (EDC/NHS) |
| BiomoleculeCompatibility | Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides |
| ResearchUse | Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation |
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