mPEG-Succinimidyl propionate
| Cat. No. | Product Name | CAS No. | |
|---|---|---|---|
| BPG-2504 | mPEG-SPA | 174569-25-6 | Inquiry |
| BPG-2897 | mPEG-Succinimidyl propionate, MW 5k-30k | Inquiry |
Synonyms: Methoxypoly(ethylene glycol) Succinimidyl propionate; Methoxy PEG SPA; mPEG SPA
The terminal of the chain of mPEG-Succinimidyl propionate is succinimide propionate. It is an amine-reactive PEG derivative that has a stable non-degradable linker between the PEG polymer chain and the NHS ester. mPEG-Succinimidyl propionate reacts with the amine group of lysine, such as those on HGH antagonist, growth hormone B2036, granulocyte colony stimulating factor MAXY-G34 (CSF MAXY-G34), or uricase. The hydrolysis half-life of mPEG-Succinimidyl propionate is longer than that of mPEG-SCM. Polyethylene glycolation increases solubility and stability and reduces the immunogenicity of peptides and proteins. It can be used to modify proteins, peptides and other materials. It also inhibits nonspecific binding of charged molecules to the modified surface.
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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Industry News
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- FDA-Approved Antibody-Drug Conjugates up to 2024
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- What is Click Chemistry?
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- What is the Formulation of Lipid Nanoparticles (LNPs)?
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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