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As an amphiphilic polymer, PEG can be soluble in water and most organic solvents, and has the characteristics of good biocompatibility, non-toxicity, and low immunogenicity. It can be wildly applied in bio-medical industry, chemical synthesis, cosmetics, textile industry, plastic industry and others.
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Technical Information
PEGylation is defined as the covalent attachment of poly(ethylene glycol) (PEG) chains to bioactive substances, such as nanoparticles, proteins, peptides or non-peptide molecules. This technology emerged gradually with progress in field of biologicals and polymer chemistry and was exploited to...
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- PEG Derivatives
- PEG Applications
- Lipid Derivatives
- Lipid Applications
- Technical Information
- Introduction of Polyethylene Glycol (PEG)
- Polyethylene Glycol (PEG) Modifier Selection Guide
- FDA approved PEGylated Products
- What are Monodispersed and Polydispersed PEGs?
- What are Biotinylation and Biotinylated PEG?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What are PEG Lipids?
- How to Perform Polyethylene Glycol (PEG) Modification?
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- PEG Purification Techniques of Plasmid DNA
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- PEG-DSPE Block Copolymers and Their Derivatives
- Preparation Method of PEG Hydrogel
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- What is Polyethylene Glycol Used For?
- Polyethylene Glycol vs. Ethylene Glycol: Understanding the Differences and Uses
PEG Applications
PEG & Bioconjugation
- Polyethylene Glycol in Antibody-Drug Conjugates
- Polyethylene Glycol in PROTAC Linkers
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- FDA-Approved Antibody-Drug Conjugates up to 2024
- The PROTAC Technology in Drug Development
- Polyethylene Glycol in Small Molecule-Drug Conjugates
- Overview of 10 Types of Drug Conjugates
- Polyethylene Glycol in Peptide-Drug Conjugates
- Polyethylene Glycol in Antibody-Oligonucleotide Conjugates
PEG & Drug Development
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- PEG for Pharmaceutical Preparation
- Polyethylene Glycol in Pharmacy
- Polyethylene Glycol for Eye Drops
- Polyethylene Glycol for Laxatives
- Polyethylene Glycol in PEGylated Interferon
PEG & Drug Delivery
PEG & Medical Devices
PEG & Click Chemistry
- What are Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- Phosphatidylcholine: Definition, Structure and Benefits
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Fatty Acids: Definition, Structure, Synthesis, Oxidation, Metabolism and Function
- What are Lipid-Drug Conjugates (LDCs)?
- What are the Monomers of Lipids?
- What is a Lipid Made of?
- Lipid Bilayer: Definition, Structure and Function
- How are Liposomes Different from Micelles?
- Overview of Liposome Preparation Process
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- What are Lipid-Based Drug Delivery Systems (LBDDS)?
- What Does A Lipid Do?
- Unraveling the Chemical Structure of Lipids: A Comprehensive Guide
- The Mystery of Lipid Synthesis: From Cells to Industrial Manufacturing
- The Science Behind Phospholipids: A Deep Dive into Their Molecular Structure
Lipid Applications
Lipid & Drug Development
Lipid & Drug Delivery
Lipid Nanoparticles & Drug Delivery
- What are Lipid Nanoparticles and Their Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Liposomes vs. Lipid Nanoparticles: What are the Differences?
- Nanoparticle-based Drug Delivery Systems: Review and Current Status
- Lipid Nanoparticles for mRNA Delivery
- Lipid Nanoparticles for Small Molecule Delivery
- Lipid Nanoparticles for Nucleic Acid Delivery
- Lipid Nanoparticles for Gene Delivery
- Lipid Nanoparticles for Ocular Drug Delivery
Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
- Enzyme-linked immunosorbent assay (ELISA) Technique
- High performance liquid chromatography (HPLC) Technique
- Hydrophobic Interaction Chromatography (HIC) Technique
- Ion Exchange Chromatography (IEX) Technique
- PEGylated Protein Purification Techniques
- Radiolabeling Technique
- SDS-PAGE Technique
- Ultrafiltration Technique
PEG for Drug Delivery
The majority of small molecule drugs, proteins and peptides, as well as liposomal and micellar nanocarriers on the market or in advanced clinical trials are PEGylated products, i.e. PEGylation.
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PEG for Pharmaceutical Preparation
PEG is a commonly used as pharmaceutical excipient, which has been widely applied in various medicaments such as soft ointment, suppository, drop pill, hard capsule, eye drop, injection and tablet.
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PEG for Cosmetic Application
PEG and PEG derivatives are widely used as humectants, solvents, binders, emulsion stabilizers, and viscosity increasing agents in a wide variety of personal care products.
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PEG for Imaging Diagnosis
PEG is a coiled polymer of repeating ethylene ether units with dynamic conformations. In both imaging and drug delivery applications, chemical modification using PEG polymers can reduce RES uptake and prolong the circulation time.
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