Azido-PEG4-amine

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Category	Small-molecule Heterobifunctional PEG
Catalog NO.	BPG-1849
Product Name	Azido-PEG4-amine
CAS	951671-92-4
Molecular Formula	C10H22N4O4
Molecular Weight	262.31

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Description	N3-PEG4-C2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. N3-PEG4-C2-NH2 can be used in the synthesis of a series of PROTACs. N3-PEG4-C2-NH2 is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
Synonyms	14-Azido-3,6,9,12-tetraoxatetradecan-1-amine; O-(2-Aminoethyl)-O'-(2-azidoethyl)triethylene Glycol; N3-PEG4-C2-NH2; N3-PEG4-CH2CH2NH2; 14-Amino-3,6,9,12-tetraoxatetradecanyl Azide; 1-Amino-14-azido-3,6,9,12-tetraoxatetradecane
IUPAC Name	2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethanamine
Canonical SMILES	C(COCCOCCOCCOCCN=[N+]=[N-])N
InChI	InChI=1S/C10H22N4O4/c11-1-3-15-5-7-17-9-10-18-8-6-16-4-2-13-14-12/h1-11H2
InChIKey	ZMBGKXBIVYXREN-UHFFFAOYSA-N
Purity	≥95%
Density	1.10 g/mL
Solubility	Soluble in DCM, DMF, DMSO, Water
Appearance	Colorless to Light Yellow to Light Orange Liquid
Storage	Store at 2-8°C
Exact Mass	262.16410520
LogP	0.47486
Pictogram(s)	Corrosive, Irritant
Signal	Danger
Precautionary Statement Codes	P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501

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