Cat. No. Product Name CAS No.
BPG-0769 Cholesterol-PEG-NHS, MW 1k-10k Inquiry

Synonyms: Cholesterol-PEG-NHS

The two ends of the CLS-PEG-NHS molecular chain are cholesterol and N-hydroxysuccinimide groups. It is a linear heterobifunctional PEG reagent, which is a lipophilic lipid PEG conjugate with good water solubility. Cholesterol can regulate the fluidity of phospholipid bilayer and reduce membrane permeability and drug leakage. It also has a protective effect on the oxidation of phospholipids. The active ester (NHS) reacts with the primary amine group between pH7~8.5 to form a fully stable amide bond. CLS-PEG-NHS can be used to make liposomes to shorten the cycle time of encapsulated drugs, as well as for non-viral transfection reagents.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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PEG linkers For Drug

Improved Circulation Half-Life

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