Cholesterol-PEG-MAL, MW 1k-10k

Name: Cholesterol-PEG-MAL, MW 1k-10k
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 923987-96-6

Cat No.: BPG-0764

4.5

Cholesterol-PEG-MAL is a heterobifunctional polyethylene glycol. It has amphipathic properties. Cholesterol can form liposomes to increase the cycle time of encapsulated drugs. The Maleimide can selectively modify proteins, peptides or any other surface. They can also be used for non-viral transfection reagents. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations.

Category	Cholesterol PEG
Molecular Weight	Customizable
Storage	-20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.

Structure of 923987-96-6

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Catalog	Molecular Weight	Availability	actions
BPG-0764-1	Cholesterol-PEG-MAL, MW 1k	In stock	Inquiry
BPG-0764-2	Cholesterol-PEG-MAL, MW 2k	In stock	Inquiry
BPG-0764-3	Cholesterol-PEG-MAL, MW 3.4k	In stock	Inquiry
BPG-0764-4	Cholesterol-PEG-MAL, MW 5k	In stock	Inquiry
BPG-0764-5	Cholesterol-PEG-MAL, MW 10k	In stock	Inquiry

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cGMP-compliant manufacturing options
Comprehensive QC testing with COA, MSD
From mg and g to kg-scale production
In-stock supply in the US and Europe
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One-stop PEGylation services
Custom PEG reagents synthesis
Click chemistry reagents
Bioconjugation & drug delivery
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Specification
Key Product Attributes
Reaction & Conjugation Properties
References

Synonyms	Cholesterol-PEG-Maleimide
Solubility	Soluble in water, DMSO and DMF. Freshly prepared before use.

PEGType	Lipid PEG
PEGArchitecture	Linear
Functionality	Monofunctional (Reactive)
LipidType	Cholesterol

ReactiveToward	Thiols
ReactionChemistry	Maleimide-Thiol Conjugation
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides
ResearchUse	Thiol-Selective Biomolecule Conjugation; Liposome / LNP Surface Functionalization

1. Maruyama, Kazuo, et al. Targeting efficiency of PEG-immunoliposome-conjugated antibodies at PEG terminals. Advanced drug delivery reviews, 1997, 24(2-3) 24.2-3: 235-242.
2. Pan, Xiaogang, et al. Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR. Bioconjugate chemistry, 2007, 18(1): 101-108.