Azido-PEG-COOH

Azido-PEG-COOH is a bifunctional PEG derivative with azide and carboxyl groups at both ends of the molecular chain. Azide group can react with alkyne in aqueous solution catalyzed by copper. When another functional group can react with other molecules or groups, it can also be easily reduced to an amine group. Azide is used to react azide group “click” chemistry in mild condition, which is very useful for bioconjugation. Polyethylene glycolation increases solubility and stability and reduces the immunogenicity of peptides and proteins. It can be used to modify proteins, peptides and other materials. It also inhibits nonspecific binding of charged molecules to the modified surface.