Synonyms: Polyethylene glycol octadecyl pyridyldisulfide

C18-PEG-OPSS is an amphiphilic diblock copolymer. It is usually a solid powder or particle, which needs to be protected by inert gas, frozen and dissolved in most organic solvents, such as DCM, DMF, DMSO, THF and so on, but also has a good solubility in water. The C18 hydrocarbon is attached to the short polyethylene glycol (PEG) through an ether bond and the PEG terminal has an OPSS (ortho-pyridyl disulfide) group, also called PDP (pyridyldisulfide propionic acid), which is reactive with thiol, sulfhydryl, mercapto, SH or cysteine.

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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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PEG linkers For Drug

Improved Circulation Half-Life

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