Synonyms: Maleimide-PEG-NH2

MAL-PEG-NH2 has a maleimide and an amino group at each end of the molecular chain and is a linear heterofunctional PEG reagent. It is a useful cross-linking reagent with PEG spacer. The maleimide contains a reactive C=C double bond and is sensitive to light or oxygen. At pH 6.5~7.5, the maleimide groups can selectively react with thiol by means of Michael addition to form stable C-S bonds. In this way, MAL-PEG-NH2 can be used to modify proteins, peptides, or other surfaces containing sulfhydryl groups. The amine can react with carboxylic acid or activated NHS ester. MAL-PEG-NH2 can also be used for the synthesis of PEGylated block copolymers. It is usually present as TFA or HCl salts.

Cat. No. Product Name CAS No.
BPG-0887 MAL-PEG-NH2, MW 1k-10k Inquiry

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