Cat. No. Product Name CAS No.
BPG-0882 MAL-PEG-COOH, MW 1k-10k Inquiry

Synonyms: Maleimide-PEG-COOH

MAL-PEG-COOH has a maleimide and a carboxyl group at each end of the molecular chain and is a linear heterofunctional PEG reagent. It is a useful cross-linking reagent with PEG spacer. The carboxyl group can react with amine or hydroxyl under standard acid/amine or acid/alcohol coupling conditions. The maleimide contains a reactive C=C double bond and is sensitive to light or oxygen. At pH 6.5~7.5, the maleimide groups can selectively react with thiol by means of Michael addition to form stable C-S bonds. In this way, MAL-PEG-COOH can be used to modify proteins, peptides, or other surfaces containing sulfhydryl groups.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
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