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HS-PEG-COOH

Cat. No. Product Name CAS No.
BPG-0862 HS-PEG-COOH, MW 1k-10k Inquiry

HS-PEG-COOH is a linear heterofunctional PEGylation reagent with thiol and carboxyl groups at the two ends of the molecular chain, respectively. It is a useful cross-linking or bioconjugation reagent with PEG spacers. The thiol can selectively react with maleimide, OPSS, vinyl sulfone and transition metal surfaces including gold and silver. The carboxyl group at the end of the PEG block is used to prepare nanoparticles and micelles for targeted drug delivery. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.

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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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APPLICATIONS

APPLICATIONS

PEG linkers For Drug

Improved Circulation Half-Life

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