MAL-PEG-SCM

Cat. No.	Product Name	CAS No.
BPG-0897	MAL-PEG-SCM, MW 1k-10k		Inquiry

Synonyms: Maleimide-PEG-SCM; Maleimide-PEG-Succinimidyl Carboxymethyl Ester; SCM-PEG-Succinimidyl Carboxymethyl Ester

MAL-PEG-SCM has a maleimide and a succinimidyl carboxyl methyl ester group at each end of the molecular chain and is a linear heterofunctional PEG reagent. It is a useful cross-linking reagent with PEG spacer. The maleimide contains a reactive C=C double bond and is sensitive to light or oxygen. At pH 6.5~7.5, the maleimide groups can selectively react with thiol by means of Michael addition to form stable C-S bonds. SCM is an NHS ester, commonly known as succinimide carboxymethyl (SCM) ester, which is highly reactive with primary amines and can form stable amide bonds. MAL-PEG-SCM can be used to introduce amine reactive functional groups into crosslinked PEG hydrogels.

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