8-Arm PEG-Epoxide

Synonyms: Eight-Arm polyethylene glycol-Epoxide; Eight-Arm PEG-Epoxide

8-Arm polyethylene glycol-Epoxide (8-Arm PEG-Epoxide) is a multiarm PEG derivative with epoxide groups at each terminal of the eight arms connected to one hexaglycerol core. It is usually a solid powder, which needs to be protected by inert gas, frozen and dissolved in some organic reagents such as dimethyl sulfoxide and dimethylformamide. Eight arm polyethylene glycol derivatives have a variety of active groups and can be used to modify a variety of materials. Terminal epoxides are often used in nucleophilic addition reactions to modify functional groups. Therefore, it is often used in targeted drug research and widely used in the cross-linking of protein carrier and ligand, etc., to increase solubility and stability.