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Boc-NH-PEG-COOH

Cat. No. Product Name CAS No.
BPG-1330 Boc-NH-PEG-COOH, MW 1k-10k Inquiry

Synonyms: Boc-NH-polyethylene glycol-COOH

Boc-NH-PEG-COOH is a linear heterobifunctional PEG reagent containing carboxyl group and Boc protected amine. It is a crosslinker with a PEG spacer group. Protected amines can be regenerated through weakly acidic conditions, such as TFA or dilute HCl. Boc-NH-PEG-COOH can be used to modify proteins, peptides and other materials by amino or other acid-reactive chemical groups. The BOC group can be de-protected under acidic conditions to release free amines for further reaction. Polyethylene glycolation increases solubility and stability and reduces the immunogenicity of peptides and proteins. It also inhibits nonspecific binding of charged molecules to the modified surface.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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APPLICATIONS

APPLICATIONS

PEG linkers For Drug

Improved Circulation Half-Life

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