Cat. No. Product Name CAS No.
BPG-0857 HO-PEG-NHS, MW 1k-10k Inquiry

HO-PEG-NHS is a linear heterobifunctional PEG derivative with one hydroxyl group and one NHS ester, which is a useful crosslinking reagent with a PEG spacer. There is a methylene (CH2) linkage between PEG and the succinimidyl carboxylate. NHS is a good leaving group and can react with the amine containing part. NHS esters react with deprotonated primary amines, and the reaction requires neutral to basic pH values to proceed. HO-PEG-NHS can be easily incorporated into liposomes and other nanoparticles through the NHS-amine reaction.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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PEG linkers For Drug

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