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OPSS-PEG-NHS

Cat. No. Product Name CAS No.
BPG-0922 OPSS-PEG-NHS, MW 1k-10k Inquiry

Synonyms: Orthopyridyl disulfide-PEG-NHS

OPSS-PEG-NHS has one OPSS and one NHS ester at each end of the molecular chain and is a linear heterofunctional PEG reagent. It is a useful cross-linking reagent with PEG spacer. OPSS stands for o-pyridinyl disulfide or o-pyridinyl disulfide, which can react with thiol, SH, sulfhydryl to form a S-S bond. Through the pyridinyl disulfide functional group, OPSS-PEG-NHS can selectively react with the sulfhydryl group to form a stable disulfide bond and release a thiol pyridyl group at the same time. NHS is a good leaving group and can act with the amine containing part.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
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