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OPSS-PEG-SCM

Cat. No. Product Name CAS No.
BPG-2817 OPSS-PEG-SCM, MW 2k-7.5k Inquiry

Synonyms: OPSS-PEG-Succinimidyl Carboxymethyl Ester; Ortho-Pyridyldisulfide-PEG-Succinimidyl Carboxymethyl Ester; Ortho-Pyridyldisulfide-PEG-SCM

OPSS-PEG-SCM is a linear heterobifunctional PEG reagent with OPSS group and NHS ester at both ends of the molecular chain. OPSS stands for o-pyridinyl disulfide or o-pyridinyl disulfide, which can react with thiol, SH, sulfhydryl to form a S-S bond. Through the pyridinyl disulfide functional group, OPSS-PEG-SCM can selectively react with the sulfhydryl group to form a stable disulfide bond and release a thiol pyridyl group at the same time. Through this reaction, It can modify biomolecules or other materials. SCM is an NHS ester, commonly known as succinimide carboxymethyl ester, which is highly reactive with primary amines and can form stable amide bonds.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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