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mPEG-PCL, PEG MW 400-10k

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Category mPEG-PCL
Catalog NO. BPG-1386
Product Name mPEG-PCL, PEG MW 400-10k
Molecular Weight Customizable
mPEG-PCL, PEG MW 400-10k
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Fast track to get specific molecular weight products:

CatalogMolecular WeightAvailability
BPG-1386-1 mPEG-PCL, PEG MW 400 In stock Inquiry
BPG-1386-2 mPEG-PCL, PEG MW 600 In stock Inquiry
BPG-1386-3 mPEG-PCL, PEG MW 1k In stock Inquiry
BPG-1386-4 mPEG-PCL, PEG MW 2k In stock Inquiry
BPG-1386-5 mPEG-PCL, PEG MW 3.4k In stock Inquiry
BPG-1386-6 mPEG-PCL, PEG MW 5k In stock Inquiry
BPG-1386-7 mPEG-PCL, PEG MW 10k In stock Inquiry
  • Product Information
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Product Information

Description Polyethylene glycol and polycaprolactone coupled compounds are widely used in the field of biomedicine. Drugs modified by the PEG-PCL series of derivatives have better water solubility, encapsulation efficiency and drug loading. PEGylation can improve the stability of the drug. PCL has good biocompatibility, degradability and other properties. It does not cause toxic side effects to the human body and can therefore be used as a carrier material for different types of drugs. In addition, PCL has good flexibility, slow degradation rate and good film formation, so it can be used for postoperative tissue engineering.
Solubility Soluble in water, DMSO and DMF. Freshly prepared before use.
Storage -20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.

mPEG-PCL (methoxy poly(ethylene glycol)-polycaprolactone), a versatile block copolymer with a broad molecular weight range spanning 400 to 10,000, is employed across diverse applications in the bioscience sector. Here, presented with high perplexity and burstiness, are four key applications of mPEG-PCL:

Drug Delivery Systems: In the intricate design landscape of drug delivery systems, mPEG-PCL shines with its exceptional biocompatibility and biodegradability attributes. Its unique ability to fashion nanoparticles or micelles that encapsulate therapeutic agents enhances solubility and stability, paving the way for controlled and sustained drug release mechanisms.

Tissue Engineering: Enter the realm of tissue engineering, where mPEG-PCL emerges as an indispensable scaffold material nurturing cell growth and fostering tissue revitalization. Boasting customizable mechanical characteristics and safe biodegradability within the body, it serves as a perfect substrate for crafting structures that mimic natural tissues. Researchers can infuse growth factors or stem cells into these scaffolds, nurturing the regeneration of damaged tissues like bone and cartilage with finesse.

Medical Devices: Diving into the realm of medical devices, mPEG-PCL plays a pivotal role in fabricating diverse implants, sutures, and wound dressings, thanks to its blend of flexibility and durability. Its robust nature makes it a favored choice for applications demanding sturdy yet pliable materials. Augmenting its appeal is its unwavering biocompatibility, ensuring minimal immune responses in medical scenarios. This adaptability firmly cements mPEG-PCL as a cornerstone in propelling medical device technology to new heights.

Cosmetic Formulations: Crossing over into the world of cosmetics, mPEG-PCL takes center stage in stabilizing and delivering potent active ingredients in formulations like creams and lotions. Its prowess in crafting stable emulsions and enhancing skin absorption of actives amplifies the efficacy of skincare products exponentially. This aids in delivering pinpoint treatments for skincare woes such as aging, hyperpigmentation, and acne, offering bespoke solutions tailored to individual skin requirements.

References 1. Gou M L, Zheng X L, Men K, et al. Self-assembled hydrophobic honokiol loaded MPEG-PCL diblock copolymer micelles.Pharmaceutical research, 2009, 26(9): 2164-2173.
2. Kim M S, Hyun H, Seo K S, et al. Preparation and characterization of MPEG-PCL diblock copolymers with thermo-responsive sol-gel-sol phase transition. Journal of Polymer Science Part A: Polymer Chemistry, 2006, 44(18): 5413-5423.

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PEGylation of Peptides and Proteins

PEGylation of Peptides
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