4-Arm PEG-SS

Synonyms: Four-Arm polyethylene glycol-succinimidyl succinate; Four-Arm PEG-SS; Four-Arm polyethylene glycol-SS

Four-Arm polyethylene glycol-succinimidyl succinate (4-Arm PEG-SS) is a multiarm PEG derivative with succinimidyl NHS ester groups at each terminal of the four arms connected to one pentaerythritol core. It is a white solid or sticky liquid, depending on its molecular weight. It is soluble in most organic solvents and has good solubility in water. It needs to be frozen, thawed slowly before use, and filled with nitrogen after use. PEG-SS (succinimidyl succinate ester) is one type of PEG-NHS reagents. There is a C2 hydrocarbon ester linkage between PEG and the NHS ester. Four arm polyethylene glycol derivatives have a variety of active groups that can be used to modify proteins, peptides and other materials through their functional groups.