Catalog NO.: BPG-1563

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Category COOH-PEGn-COOtBu
Product Name COOH-PEG6-COOtBu
CAS 2093153-84-3
Molecular Formula C20H38O10
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Product Information

Description COOH-PEG6-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms Acid-PEG6-t-butyl ester; Acid-PEG6-C2-Boc; HOOCCH2CH2O-PEG5-CH2CH2COOtBu; COOH-PEG6-OtBu; 2,2-Dimethyl-4-oxo-3,7,10,13,16,19,22-heptaoxapentacosan-25-oic acid; 4,7,10,13,16,19-Hexaoxadocosane-1,22-dioic acid, mono(1,1-dimethylethyl) ester
IUPAC Name 3-[2-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Molecular Weight 438.51
Molecular Formula C20H38O10
InChI InChI=1S/C20H38O10/c1-20(2,3)30-19(23)5-7-25-9-11-27-13-15-29-17-16-28-14-12-26-10-8-24-6-4-18(21)22/h4-17H2,1-3H3,(H,21,22)
Boiling Point 528.9±50.0°C at 760 mmHg
Purity ≥95%
Density 1.1±0.1 g/cm3
Solubility Soluble in DCM, DMF, DMSO, Water
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C


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