COOH-PEG1-COOtBu
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| Category | COOH-PEGn-COOtBu |
| Catalog NO. | BPG-0187 |
| Product Name | COOH-PEG1-COOtBu |
| CAS | 2086689-08-7 |
| Molecular Formula | C10H18O5 |
| Molecular Weight | 218.25 |
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Product Information
| Description | COOH-PEG1-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. |
| Synonyms | Acid-PEG1-t-butyl ester; Acid-PEG1-C2-Boc; 3-(3-(tert-butoxy)-3-oxopropoxy)propanoic acid; Propanoic acid, 3-(2-carboxyethoxy)-, 1-(1,1-dimethylethyl) ester; 3-(2-Carboxyethoxy)propanoic acid 1-tert-butyl ester; 3-{3-[(2-Methyl-2-propanyl)oxy]-3-oxopropoxy}propanoic acid; Propanoic acid, 3,3'-oxybis-, 1,1-dimethylethyl ester |
| IUPAC Name | 3-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]propanoic acid |
| SMILES | CC(C)(C)OC(=O)CCOCCC(=O)O |
| InChI | InChI=1S/C10H18O5/c1-10(2,3)15-9(13)5-7-14-6-4-8(11)12/h4-7H2,1-3H3,(H,11,12) |
| InChIKey | ZDYGOKORAHMWLC-UHFFFAOYSA-N |
| Boiling Point | 341.9±22.0°C (Predicted) |
| Purity | ≥95% |
| Density | 1.101±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
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