COOH-PEG4-COOtBu
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| Category | COOH-PEGn-COOtBu |
| Catalog NO. | BPG-0186 |
| Product Name | COOH-PEG4-COOtBu |
| CAS | 1835759-85-7 |
| Molecular Formula | C16H30O8 |
| Molecular Weight | 350.41 |
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Product Information
| Description | COOH-PEG4-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. |
| Synonyms | Acid-PEG4-t-butyl ester; Acid-PEG4-C2-Boc; COOH-PEG4-OtBu; HOOCCH2CH2O-PEG3-CH2CH2COOtBu; 2,2-Dimethyl-4-oxo-3,7,10,13,16-pentaoxanonadecan-19-oic acid; 4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) ester; 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, mono(1,1-dimethylethyl) ester |
| IUPAC Name | 3-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C16H30O8/c1-16(2,3)24-15(19)5-7-21-9-11-23-13-12-22-10-8-20-6-4-14(17)18/h4-13H2,1-3H3,(H,17,18) |
| InChIKey | LXMHKDZTUDTSCT-UHFFFAOYSA-N |
| Boiling Point | 460.1±40.0°C (Predicted) |
| Purity | ≥95% |
| Density | 1.107±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Storage | Store at 2-8°C |
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