Fmoc-N-amido-PEG1-acid

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Category	Small-molecule Group Protected PEG
Catalog NO.	BPG-2016
Product Name	Fmoc-N-amido-PEG1-acid
CAS	1654740-73-4
Molecular Formula	C20H21NO5
Molecular Weight	355.38

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Description	Fmoc-N-amido-PEG1-acid is a PEG linker containing a Fmoc-protected amine and a terminal carboxylic acid. The Fmoc group can be deprotected under the basic conditions to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms	Fmoc-6-Amino-4-oxahexanoic acid; Fmoc-N-amido-PEG1-acid; Fmoc-NH-PEG1-C2-acid; Fmoc-NH-PEG1-CH2CH2COOH; 6-(Fmoc-amino)-4-oxahexanoic Acid; Fmoc-AEP; Fmoc-PEG1-propionic acid; Propanoic acid, 3-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]-; 3-[2-(Fmoc-amino)ethoxy]propanoic acid
IUPAC Name	3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]propanoic acid
Canonical SMILES	C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCC(=O)O
InChI	InChI=1S/C20H21NO5/c22-19(23)9-11-25-12-10-21-20(24)26-13-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,18H,9-13H2,(H,21,24)(H,22,23)
InChIKey	LHBCOPWWQKLECJ-UHFFFAOYSA-N
Boiling Point	589.9±40.0 °C at 760 mmHg
Purity	>98%
Density	1.261±0.06 g/cm3 (Predicted)
Solubility	Soluble in DMSO
Appearance	Pale Yellow or Colorless Oily Matter
Storage	Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Exact Mass	355.14197277

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