| Category | Fmoc-N-amido-PEGn-acid |
| Molecular Formula | C34H49NO12 |
| Molecular Weight | 663.75 |
| Appearance | Colourless to pale yellow liquid |
| Shipping | Room temperature, or blue ice upon request. |
| Storage | Store at -20°C, keep in dry and avoid sunlight |
Fmoc-N-amido-PEG8-propionic acid
Fmoc-N-amido-PEG8-propionic acid combines Fmoc protective groups with an 8-unit PEG spacer, optimizing ADC linker stability and solubility. This intermediate supports precise antibody conjugation and controlled drug release in targeted antibody-drug conjugates.
Structure of 756526-02-0
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- Specification
| Synonyms | Fmoc-N-amido-PEG8-acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid; Fmoc-NH-PEG8-CH2CH2COOH; 1-(Fmoc-amino)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic Acid; Fmoc-PEG8-propionic acid; 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9-fluren-9-ylmethyl)ester; 2,7,10,13,16,19,22,25,28-Nonaoxa-4-azahentriacontan-31-oic acid, 1-(9H-fluoren-9-yl)-3-oxo- |
| IUPACName | 3-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| CanonicalSMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C34H49NO12/c36-33(37)9-11-39-13-15-41-17-19-43-21-23-45-25-26-46-24-22-44-20-18-42-16-14-40-12-10-35-34(38)47-27-32-30-7-3-1-5-28(30)29-6-2-4-8-31(29)32/h1-8,32H,9-27H2,(H,35,38)(H,36,37) |
| InChIKey | VYXGUCLTEWCVRY-UHFFFAOYSA-N |
| BoilingPoint | 781.1±60.0 °C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.190±0.06 g/cm3 |
| Solubility | Soluble in DMSO (10 mm) |
| RelatedCAS | <a href="/product/fmoc-n-amido-peg36-propionic-acid-cas-850312-72-0-153372.html">850312-72-0</a> (polymer) |
| ExactMass | 663.325476 |
| LogP | 3.52350 |
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