| Category | Fmoc-N-amido-PEGn-acid |
| Molecular Formula | C26H33NO8 |
| Molecular Weight | 487.54 |
| Appearance | Pale Yellow or Colorless Oily Matter |
| Shipping | Room temperature |
| Storage | Store at -20°C, keep in dry and avoid sunlight |
Fmoc-N-amido-PEG4-propionic acid
Fmoc-N-amido-PEG4-propionic acid is a PEG-based spacer and synthetic linker building block used to introduce a defined hydrophilic and flexible segment into multistep conjugation designs. The PEG chain can increase molecular spacing and provide a modular connection between reactive groups without serving as a dedicated cleavage trigger. This derivative contains peg4 spacer together with terminal functionality selected for further synthesis. The available reactive group is no dedicated antibody-reactive group unless activated/functionalized; terminal functionality depends on the specific peg derivative. The opposite terminus provides terminal carboxylic acid; activate for coupling to an amine-bearing payload. Coupling and deprotection conditions should be matched to the terminal groups and the intended order of assembly.
Structure of 557756-85-1
Ordering Information
*For research and manufacturing use only. We do not sell to patients.
| Catalog Number | Name | Size / Price | Stock | Quantity | |
|---|---|---|---|---|---|
| BPG-2243 | Fmoc-N-amido-PEG4-propionic acid | In stock |
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- Specification
| Synonyms | 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid; Fmoc-N-amido-PEG4-acid; Fmoc-NH-PEG4-CH2CH2COOH; Fmoc-15-Amino-4,7,10,13-tetraoxapentadecacanoic acid; 2,7,10,13,16-Pentaoxa-4-azanonadecan-19-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-; 15-(9-Fluorenylmethyloxycarbonyl)amino-4,7,10,13-tetraoxa-pentadecanoic acid; 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester; 15-(Fmoc-amino)-4,7,10,13-tetraoxapentadecanoic Acid |
| IUPACName | 3-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| CanonicalSMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29) |
| InChIKey | NUHRPLKTAAVHCZ-UHFFFAOYSA-N |
| BoilingPoint | 682.1±55.0 °C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.219 g/cm3 |
| Solubility | Soluble in DCM, DMF, DMSO |
| RelatedCAS | <a href="/product/fmoc-n-amido-peg36-propionic-acid-cas-850312-72-0-153372.html">850312-72-0</a> (polymer) |
| ShelfLife | ≥ 2 years |
| LogP | 3.45710 |
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