| Category | Fmoc-N-amido-PEGn-acid |
| Molecular Formula | C36H53NO13 |
| Molecular Weight | 707.80 |
| Appearance | Pale Yellow or Colorless Oily Liquid |
| Shipping | Room temperature |
| Storage | Store at 2-8°C |
Fmoc-N-amido-PEG9-acid
Fmoc-N-amido-PEG9-acid is a high-performance ADC linker featuring a PEG9 spacer that enhances solubility and flexibility. It facilitates efficient and stable drug-antibody conjugation, making it ideal for targeted cancer therapy development.
Structure of 1191064-81-9
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | Fmoc-NH-PEG9-CH2CH2COOH; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31-decaoxa-4-azatetratriacontan-34-oic acid; Fmoc-NH-PEG9-acid; Fmoc-PEG9-propionic acid; 1-(Fmoc-amino)-3,6,9,12,15,18,21,24,27-nonaoxa-30-triacontanoic Acid; 5,8,11,14,17,20,23,26,29-Nonaoxa-2-azadotriacontanedioic acid 1-(9H-fluoren-9-ylmethyl) ester; 2,7,10,13,16,19,22,25,28,31-Decaoxa-4-azatetratriacontan-34-oic acid, 1-(9H-fluoren-9-yl)-3-oxo- |
| IUPACName | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| CanonicalSMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C36H53NO13/c38-35(39)9-11-41-13-15-43-17-19-45-21-23-47-25-27-49-28-26-48-24-22-46-20-18-44-16-14-42-12-10-37-36(40)50-29-34-32-7-3-1-5-30(32)31-6-2-4-8-33(31)34/h1-8,34H,9-29H2,(H,37,40)(H,38,39) |
| InChIKey | NEESTRVILHNOJT-UHFFFAOYSA-N |
| BoilingPoint | 803.9±65.0 °C at 760 mmHg |
| FlashPoint | 440.0±34.3 °C |
| Purity | ≥95% |
| Density | 1.186±0.06 g/cm3 at 20°C, 760 Torr |
| Solubility | Soluble in DCM, DMF, DMSO |
| RelatedCAS | 850312-72-0 (polymer) |
| ShelfLife | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| VaporPressure | 0.0±3.0 mmHg at 25°C |
| LogP | 0.51 |
| PEGType | Discrete PEG Linker |
| PEGArchitecture | Linear |
| Functionality | Monofunctional (Reactive) |
| ProtectingGroup | Fmoc |
| ReactiveToward | Primary Amines (after activation) |
| ReactionChemistry | Carbodiimide-Mediated Amide Coupling (EDC/NHS) |
| BiomoleculeCompatibility | Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides |
| ResearchUse | Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation |
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