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N,N'-DME-N-PEG2-Boc
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| Category | N,N'-DME-N-PEGn-Boc |
| Catalog NO. | BPG-0553 |
| Product Name | N,N'-DME-N-PEG2-Boc |
| CAS | 2279944-69-1 |
| Molecular Formula | C15H32N2O4 |
| Molecular Weight | 304.43 |
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| Description | N,N'-DME-N-PEG2-Boc is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs. |
| Synonyms | N,N'-DME-N-PEG2-tert-butyl ester; tert-Butyl 5-methyl-8,11-dioxa-2,5-diazatetradecan-14-oate; 2-Methyl-2-propanyl 5-methyl-8,11-dioxa-2,5-diazatetradecan-14-oate; 8,11-Dioxa-2,5-diazatetradecan-14-oic acid, 5-methyl-, 1,1-dimethylethyl ester |
| IUPAC Name | tert-butyl 3-[2-[2-[methyl-[2-(methylamino)ethyl]amino]ethoxy]ethoxy]propanoate |
| Canonical SMILES | CC(C)(C)OC(=O)CCOCCOCCN(C)CCNC |
| InChI | InChI=1S/C15H32N2O4/c1-15(2,3)21-14(18)6-10-19-12-13-20-11-9-17(5)8-7-16-4/h16H,6-13H2,1-5H3 |
| InChIKey | VROYCYWEWWSVEE-UHFFFAOYSA-N |
| Boiling Point | 374.7±27.0°C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.0±0.1 g/cm3 |
| Appearance | Pale Yellow Oily Matter |
| Storage | Store at 2-8°C, protect from light |
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Resources
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Technical Information
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
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- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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