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N-(2-Hydroxyethyl)maleimide

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Category Mal-PEGn-OH
Catalog NO. BPG-3589
Product Name N-(2-Hydroxyethyl)maleimide
CAS 1585-90-6
Molecular Formula C6H7NO3
Molecular Weight 141.12
N-(2-Hydroxyethyl)maleimide
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Description N-(2-Hydroxyethyl)maleimide is a PEG linker containing a maleimide group and a hydroxyl group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of a biomolecule with a thiol. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms Mal-PEG1-OH; Maleimide-PEG1-alcohol; 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione; 1-(2-hydroxyethyl)-2,5-dihydro-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 1-(2-hydroxyethyl)-; 2-Maleimidylethanol
IUPAC Name 1-(2-hydroxyethyl)pyrrole-2,5-dione
Canonical SMILES C1=CC(=O)N(C1=O)CCO
InChI InChI=1S/C6H7NO3/c8-4-3-7-5(9)1-2-6(7)10/h1-2,8H,3-4H2
InChIKey AXTADRUCVAUCRS-UHFFFAOYSA-N
Boiling Point 130°C at 0.005 mmHg
Melting Point 66-67°C
Purity ≥95%
Density 1.395 g/cm3
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C
Exact Mass 141.042593085

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