N-(2-Hydroxyethyl)maleimide

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Category	Mal-PEGn-OH
Catalog NO.	BPG-3589
Product Name	N-(2-Hydroxyethyl)maleimide
CAS	1585-90-6
Molecular Formula	C6H7NO3
Molecular Weight	141.12

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Description	N-(2-Hydroxyethyl)maleimide is a PEG linker containing a maleimide group and a hydroxyl group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of a biomolecule with a thiol. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms	Mal-PEG1-OH; Maleimide-PEG1-alcohol; 1-(2-Hydroxyethyl)-1H-pyrrole-2,5-dione; 1-(2-hydroxyethyl)-2,5-dihydro-1H-pyrrole-2,5-dione; 1H-Pyrrole-2,5-dione, 1-(2-hydroxyethyl)-; 2-Maleimidylethanol
IUPAC Name	1-(2-hydroxyethyl)pyrrole-2,5-dione
Canonical SMILES	C1=CC(=O)N(C1=O)CCO
InChI	InChI=1S/C6H7NO3/c8-4-3-7-5(9)1-2-6(7)10/h1-2,8H,3-4H2
InChIKey	AXTADRUCVAUCRS-UHFFFAOYSA-N
Boiling Point	130°C at 0.005 mmHg
Melting Point	66-67°C
Purity	≥95%
Density	1.395 g/cm³
Related CAS	58914-60-6 (polymer) 894072-45-8 (polymer) 2569686-51-5 (polymer)
Appearance	Pale Yellow or Colorless Oily Matter
Storage	Store at 2-8°C
Exact Mass	141.042593085
LogP	-1.15840
Pictogram(s)	Irritant
Signal	Warning
Precautionary Statement Codes	P264+P265, P280, P305+P351+P338, and P337+P317

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