Lipoamide-PEG1-Mal
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| Category | Lipoamide-PEGn-Mal |
| Catalog NO. | BPG-0284 |
| Product Name | Lipoamide-PEG1-Mal |
| Molecular Formula | C19H29N3O5S2 |
| Molecular Weight | 443.58 |
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| Description | Lipoamide-PEG1-Mal is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs. |
| Synonyms | LA-PEG1-NH-Mal; Lipoamide-PEG1-NH-Mal; MAL-PEG1-Lipoamide |
| IUPAC Name | N-(2-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)ethyl)-5-(1,2-dithiolan-3-yl)pentanamide |
| Canonical SMILES | O=C(NCCOCCNC(CCN1C(C=CC1=O)=O)=O)CCCCC2SSCC2 |
| InChI | InChI=1S/C19H29N3O5S2/c23-16(4-2-1-3-15-8-14-28-29-15)20-9-12-27-13-10-21-17(24)7-11-22-18(25)5-6-19(22)26/h5-6,15H,1-4,7-14H2,(H,20,23)(H,21,24) |
| InChIKey | ZORFFPHJQVCNSF-UHFFFAOYSA-N |
| Purity | ≥95% |
| Related CAS | 2767245-00-9 (polymer) |
| Storage | Store at 2-8°C |
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Technical Information
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Industry News
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- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
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