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Tetraethylene glycol bis(p-toluenesulfonate)

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Category Small-molecule Homobifunctional PEG
Catalog NO. BPG-2268
Product Name Tetraethylene glycol bis(p-toluenesulfonate)
CAS 37860-51-8
Molecular Formula C22H30O9S2
Molecular Weight 502.60
Tetraethylene glycol bis(p-toluenesulfonate)
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Description Tetraethylene glycol bis(p-toluenesulfonate) is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs.
Synonyms Tos-PEG5-Tos; Tos-PEG4-Tos; ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(4-Methylbenzenesulfonate); Tetraethylene glycol ditosylate; Tetraethylene Glycol Di-p-tosylate; Tetraethylene Glycol Bis(p-toluenesulfonate); 2,2'-(Ethylenedioxy)triethyl ditosylate; 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane; Bis[2-(2-tosyloxyethoxy)ethyl] Ether; Bis[2-[2-(p-toluenesulfonyloxy)ethoxy]ethyl] Ether; Ethanol, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-, bis(4-methylbenzenesulfonate)
IUPAC Name 2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Canonical SMILES CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)C2=CC=C(C=C2)C
InChI InChI=1S/C22H30O9S2/c1-19-3-7-21(8-4-19)32(23,24)30-17-15-28-13-11-27-12-14-29-16-18-31-33(25,26)22-9-5-20(2)6-10-22/h3-10H,11-18H2,1-2H3
InChIKey SLAONPBUWDUSSO-UHFFFAOYSA-N
Boiling Point 635.0±55.0°C (Predicted)
Melting Point 65-69°C
Purity >95%
Density 1.242 g/mL at 25°C
Solubility 10 mM in DMSO
Appearance Colorless to Yellow Clear Liquid
Storage Store at 2-8°C
Exact Mass 502.13312488

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