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PhotoClick Sphingosine

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Category Click Reagents
Catalog NO. BPG-3019
Product Name PhotoClick Sphingosine
CAS 1823021-14-2
Molecular Formula C19H33N3O2
Molecular Weight 335.49
PhotoClick Sphingosine
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Product Information

Description PhotoClick Sphingosine is used as a platform for targeted drug delivery, specifically in the treatment of cancer and inflammatory diseases. This molecule allows for precise spatial and temporal control of drug release within the body, enhancing treatment efficacy while minimizing systemic side effects.
Synonyms (2S,3R,E)-2-amino-13-(3-(pent-4-yn-1-yl)-3H-diazirin-3-yl)tridec-4-ene-1,3-diol
IUPAC Name (E,2S,3R)-2-amino-13-(3-pent-4-ynyldiazirin-3-yl)tridec-4-ene-1,3-diol
Canonical SMILES C#CCCCC1(N=N1)CCCCCCCCC=CC(C(CO)N)O
InChI InChI=1S/C19H33N3O2/c1-2-3-11-14-19(21-22-19)15-12-9-7-5-4-6-8-10-13-18(24)17(20)16-23/h1,10,13,17-18,23-24H,3-9,11-12,14-16,20H2/b13-10+/t17-,18+/m0/s1
InChIKey CNCJUDANJBAFRY-WOKGBUJHSA-N
Boiling Point 488.6±55.0 °C at 760 mmHg
Purity >99%
Density 1.1±0.1 g/cm3
Appearance Powder
Shelf Life 1 Year
Storage Store at -20°C
Exact Mass 335.26
Hygroscopic No
Light Sensitive No
Percent Composition C 68.02%, H 9.91%, N 12.53%, O 9.54%
References 1. Höglinger D. Bi- and Trifunctional Lipids for Visualization of Sphingolipid Dynamics within the Cell. Methods Mol Biol. 2019;1949:95-103. doi: 10.1007/978-1-4939-9136-5_8. PubMed ID: 30790251.
2. Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C. Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions. ACS Chem Biol. 2016 Jan 15;11(1):222-30. doi: 10.1021/acschembio.5b00810. Epub 2015 Nov 25. PubMed ID: 26555438.

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