24(R)-hydroxycholesterol

Name: 24(R)-hydroxycholesterol
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 27460-26-0

Cat No.: BPG-3291

Purity: ≥98%

4.5

24(S)-Hydroxy cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis. 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXRα and LXRβ nuclear receptors with slightly reduced potency.

Category	Cholesterol
Molecular Formula	C27H46O2
Molecular Weight	402.65
Appearance	White to Off-white Solid
Storage	Store at -20°C

Structure of 27460-26-0

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Specification
References

Synonyms	(24R)-cholest-5-ene-3beta,24-diol; (3beta,24R)-Cholest-5-ene-3,24-diol
IUPACName	(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
CanonicalSMILES	CC(C)C(CCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)O
InChI	InChI=1S/C27H46O2/c1-17(2)25(29)11-6-18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20+,21+,22-,23+,24+,25-,26+,27-/m1/s1
InChIKey	IOWMKBFJCNLRTC-RNCHBCSGSA-N
BoilingPoint	513.1±23.0 °C at 760 mmHg
MeltingPoint	184-187°C
Purity	≥98%
Density	1.03±0.1 g/cm3
Solubility	Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly)
ShelfLife	1 Year
ExactMass	402.35
Hygroscopic	No
LightSensitive	No
PercentComposition	C 80.54%, H 11.51%, O 7.95%