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Hydroxy-PEG4-propionic acid

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Category Small-molecule Heterobifunctional PEG
Catalog NO. BPG-1857
Product Name Hydroxy-PEG4-propionic acid
CAS 937188-59-5
Molecular Formula C11H22O7
Molecular Weight 266.29
Hydroxy-PEG4-propionic acid
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Product Information

Description Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms OH-PEG4-COOH; HO-PEG4-Propionic acid; HO-PEG4-CH2CH2COOH; Hydroxy-PEG4-acid; 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid; 15-Hydroxy-4,7,10,13-tetraoxapentadecanoic Acid; α,ω-hydroxy-propionic acid tetraethylene glycol; 4,7,10,13-Tetraoxapentadecanoic acid, 15-hydroxy-; 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy-
IUPAC Name 3-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES C(COCCOCCOCCOCCO)C(=O)O
InChI InChI=1S/C11H22O7/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h12H,1-10H2,(H,13,14)
InChIKey UQWLGZFJGVEDCQ-UHFFFAOYSA-N
Boiling Point 420.7±40.0 °C at 760 mmHg
Flash Point 155.5±20.8 °C
Purity >98.0%
Density 1.169±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO
Appearance Pale Yellow or Colorless Oily Matter
Shelf Life -20℃ 3 years powder; -80℃ 2 years in solvent
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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