Fmoc-N-amido-PEG2-acetic acid

Name: Fmoc-N-amido-PEG2-acetic acid
Brand: BOC Sciences
Price: 299 USD
Availability: MadeToOrder

CAS No.: 166108-71-0

Cat No.: BPG-2062

Purity: 98%

4.5

Fmoc-N-amido-PEG2-acetic acid is a PEG-based spacer and synthetic linker building block used to introduce a defined hydrophilic and flexible segment into multistep conjugation designs. The PEG chain can increase molecular spacing and provide a modular connection between reactive groups without serving as a dedicated cleavage trigger. This derivative contains peg2 spacer together with terminal functionality selected for further synthesis. The available reactive group is no dedicated antibody-reactive group unless activated/functionalized; terminal functionality depends on the specific peg derivative. The opposite terminus provides terminal carboxylic acid; activate for coupling to an amine-bearing payload. Coupling and deprotection conditions should be matched to the terminal groups and the intended order of assembly.

Category	Fmoc-NH-PEGn-CH2COOH
Molecular Formula	C21H23NO6
Molecular Weight	385.41
Appearance	Pale Yellow or Colorless Oily Matter
Shipping	Room temperature, or blue ice upon request.
Storage	Store at 2-8°C under inert atmosphere

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Structure of 166108-71-0

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Catalog Number	Name	Size / Price	Stock	Quantity
BPG-2062	Fmoc-N-amido-PEG2-acetic acid		In stock
BPG-2062	Fmoc-N-amido-PEG2-acetic acid		In stock

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Specification

Synonyms	Fmoc-NH-PEG2-CH2COOH; Fmoc-8-amino-3,6-dioxaoctanoic acid; [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid; FMOC-AEEA; 12- (9H- Fluoren- 9- yl) - 10- oxo-3, 6, 11- trioxa- 9- azadodecanoic Acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic Acid; 8-(9-Fluorenylmethoxycarbonylamino)-3,6-dioxaoctanoic Acid; 9-Fluorenylmethoxycarbonyl-8-amino-3,6-dioxaoctanoic Acid; 2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
IUPACName	2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
CanonicalSMILES	C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCC(=O)O
InChI	InChI=1S/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24)
InChIKey	XQPYRJIMPDBGRW-UHFFFAOYSA-N
BoilingPoint	631.4±45.0°C (Predicted)
MeltingPoint	85-102°C
FlashPoint	335.6±28.7 °C
Purity	98%
Density	1.265±0.06 g/cm3 (Predicted)
Solubility	Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
RelatedCAS	<a href="/product/fmoc-nh-peg12-ch2cooh-cas-675606-79-8-448604.html">675606-79-8</a> (polymer)
ShelfLife	-20°C 3 years powder; -80°C 2 years in solvent
VaporPressure	0.0±1.9 mmHg at 25°C
LogP	2.63
Pictogram	Irritant
Signal	Warning
PrecautionaryStatementCodes	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501