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Fmoc-N-amido-PEG2-acetic acid

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Category Small-molecule Group Protected PEG
Catalog NO. BPG-2062
Product Name Fmoc-N-amido-PEG2-acetic acid
CAS 166108-71-0
Molecular Formula C21H23NO6
Molecular Weight 385.41
Fmoc-N-amido-PEG2-acetic acid

Ordering Information

Catalog Number Size Price Stock Quantity
BPG-2062 10 g $299 In stock
BPG-2062 100 g $1364 In stock
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Product Information

Description Fmoc-AEEA-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms Fmoc-NH-PEG2-CH2COOH; Fmoc-8-amino-3,6-dioxaoctanoic acid; [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid; FMOC-AEEA; 12- (9H- Fluoren- 9- yl) - 10- oxo-3, 6, 11- trioxa- 9- azadodecanoic Acid; 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azadodecan-12-oic Acid; 8-(9-Fluorenylmethoxycarbonylamino)-3,6-dioxaoctanoic Acid; 9-Fluorenylmethoxycarbonyl-8-amino-3,6-dioxaoctanoic Acid; 2,7,10-Trioxa-4-azadodecan-12-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
IUPAC Name 2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]acetic acid
Canonical SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCC(=O)O
InChI InChI=1S/C21H23NO6/c23-20(24)14-27-12-11-26-10-9-22-21(25)28-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-8,19H,9-14H2,(H,22,25)(H,23,24)
InChIKey XQPYRJIMPDBGRW-UHFFFAOYSA-N
Boiling Point 631.4±45.0°C (Predicted)
Melting Point 85-102°C
Flash Point 335.6±28.7 °C
Purity 98%
Density 1.265±0.06 g/cm3 (Predicted)
Solubility Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Related CAS 675606-79-8 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Shelf Life -20°C 3 years powder; -80°C 2 years in solvent
Storage Store at 2-8°C under inert atmosphere
Vapor Pressure 0.0±1.9 mmHg at 25°C
LogP 2.63
Pictogram(s) Irritant
Signal Warning
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501

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