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tert-butyl ester-PEG12-aldehyde

Cat No. Cat No.: BPG-2465
4.5 Reviews Start

tert-butyl ester-PEG12-aldehyde is a PEG linker containing a tert-butyl ester and an aldehyde group. The aldehyde is an amine-reactive group that can form conjugates with proteins and peptides. The carboxyl group is protected by the tert-butyl group.

Category Small-molecule Group Protected PEG
Molecular Formula C31H60O15
Molecular Weight 672.8
Appearance Liquid
Storage Store at -20°C
tert-butyl ester-PEG12-aldehyde

Structure of tert-butyl ester-PEG12-aldehyde

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  • Specification
  • Key Product Attributes
  • Reaction & Conjugation Properties
Synonyms Ald-PEG12-t-butyl ester; Aldehyde-PEG12-t-butyl ester; Ald-PEG12-CH2CH2COOtBu
PEGType Discrete PEG Linker
PEGArchitecture Linear
Functionality Monofunctional (Reactive)
ProtectingGroup tBu
ReactiveToward Aminooxy Groups; Hydrazides / Hydrazines; Primary Amines
ReactionChemistry Oxime Ligation; Hydrazone Formation; Reductive Amination
BiomoleculeCompatibility Carbonyl-Reactive Proteins / Peptides; Glycans / Oxidized Glycoproteins; Aminooxy- or Hydrazide-Modified Oligonucleotides
ResearchUse Carbonyl–Aminooxy Oxime Ligation; Carbonyl–Hydrazide Ligation; Carbonyl–Amine Reductive Amination

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