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Polymethacrylate Copolymer

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Category Polymers & Polymerizable Lipids
Catalog NO. BPG-3004
Product Name Polymethacrylate Copolymer
CAS 2315261-99-3
Molecular Formula C21H40NO6S+
Polymethacrylate Copolymer
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Description The advantages of PMA based lipid nanodiscs: PMA is more stable than SMA at lower pH and in the presence of divalent metal ions, PMA has a mild effect on lipid acyl chains, spontaneously forms lipid nanodiscs through fragmentation of the lipid bilayer, larger PMA polymer nanodiscs can be aligned in a magnetic field allowing for solid-state NMR studies on membrane proteins or peptides.
Synonyms Polymethacrylate Copolymer (N−C4−52−6.9); PMA
Purity >99%
Appearance White Solid
Storage Store at -20°C
Hygroscopic No
Light Sensitive No
Percent Composition Fraction of Butyl Methacrylate (BMA) in Copolymer: ~0.52Fraction of Methyl Acryoloxy Choline (MAC) in Copolymer: ~0.48Degree of Polymerization (DP): ~39.00
References 1. Yasuhara K, Arakida J, Ravula T, Ramadugu SK, Sahoo B, Kikuchi JI, Ramamoorthy A. Spontaneous Lipid Nanodisc Fomation by Amphiphilic Polymethacrylate Copolymers. J Am Chem Soc. 2017 Dec 27;139(51):18657-18663. doi: 10.1021/jacs.7b10591. Epub 2017 Dec 5. PubMed ID: 29171274.

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