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Polymethacrylate Copolymer
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| Category | Polymers & Polymerizable Lipids |
| Catalog NO. | BPG-3004 |
| Product Name | Polymethacrylate Copolymer |
| CAS | 2315261-99-3 |
| Molecular Formula | C21H40NO6S+ |
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| Description | The advantages of PMA based lipid nanodiscs: PMA is more stable than SMA at lower pH and in the presence of divalent metal ions, PMA has a mild effect on lipid acyl chains, spontaneously forms lipid nanodiscs through fragmentation of the lipid bilayer, larger PMA polymer nanodiscs can be aligned in a magnetic field allowing for solid-state NMR studies on membrane proteins or peptides. |
| Synonyms | Polymethacrylate Copolymer (N−C4−52−6.9); PMA |
| Purity | >99% |
| Appearance | White Solid |
| Storage | Store at -20°C |
| Hygroscopic | No |
| Light Sensitive | No |
| Percent Composition | Fraction of Butyl Methacrylate (BMA) in Copolymer: ~0.52Fraction of Methyl Acryoloxy Choline (MAC) in Copolymer: ~0.48Degree of Polymerization (DP): ~39.00 |
| References | 1. Yasuhara K, Arakida J, Ravula T, Ramadugu SK, Sahoo B, Kikuchi JI, Ramamoorthy A. Spontaneous Lipid Nanodisc Fomation by Amphiphilic Polymethacrylate Copolymers. J Am Chem Soc. 2017 Dec 27;139(51):18657-18663. doi: 10.1021/jacs.7b10591. Epub 2017 Dec 5. PubMed ID: 29171274. |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
- How are Liposomes Different from Micelles?
- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
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- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
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