mPEG7-CH2CH2COONHS ester

Name: mPEG7-CH2CH2COONHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 756525-90-3

Cat No.: BPG-2278

Purity: >98.0%

4.5

mPEG7-CH2CH2COONHS ester is a PEG-based spacer and synthetic linker building block used to introduce a defined hydrophilic and flexible segment into multistep conjugation designs. The PEG chain can increase molecular spacing and provide a modular connection between reactive groups without serving as a dedicated cleavage trigger. This derivative contains peg7 spacer together with terminal functionality selected for further synthesis. The available reactive group is nhs/succinimidyl ester (amine-reactive) for antibody lysines/primary amines. The opposite terminus provides terminal peg functionality depends on the specific derivative; additional activation may be required. Coupling and deprotection conditions should be matched to the terminal groups and the intended order of assembly.

Category	Small-molecule Methoxy Linear PEG (mPEG)
Molecular Formula	C22H39NO12
Molecular Weight	509.54
Appearance	Colorless to yellow clear liquid
Shipping	Room temperature, or blue ice upon request.
Storage	Store at -20 °C, keep in dry and avoid sunlight.

Structure of 756525-90-3

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Specification

Synonyms	2,5-DIOXOPYRROLIDIN-1-YL 2,5,8,11,14,17,20,23-OCTAOXAHEXACOSAN-26-OATE; MeO-dPEG(8)-NHS; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate; mPEG7-NHS ester; m-dPEG(R)8-NHS ester; mPEG7-CH2CH2COONHS; 4,7,10,13,16,19,22,25-Octaoxahexacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester; N-Succinimidyl 4,7,10,13,16,19,22,25-Octaoxahexacosanoate; 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid succinimidyl ester; 4,7,10,13,16,19,22,25-Octaoxahexacosanoic Acid N-Succinimidyl Ester; 1-[(26-Oxo-2,5,8,11,14,17,20,23-octaoxahexacosan-26-yl)oxy]pyrrolidine-2,5-dione
IUPACName	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CanonicalSMILES	COCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChI	InChI=1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
InChIKey	IBZNTYBFTKFSMU-UHFFFAOYSA-N
BoilingPoint	567.6±60.0 °C at 760 mmHg
Purity	>98.0%
Density	1.2±0.1 g/cm3
Solubility	10 mm in DMSO
ShelfLife	≥ 2 years