MAL-PEG-Silane, MW 1k-10k

Name: MAL-PEG-Silane, MW 1k-10k
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-0902

4.5

MAL-PEG-Silane has two different activated terminal groups. Maleimide can modify the thiol group. A stable oxime ether bond is formed with the thiol group at a pH of 6.5-7.5. Under copper catalysis, azide can undergo a click chemical reaction with an alkyne group in an aqueous solution to form a nitrogen-containing five-membered heterocyclic ring. Silane can modify the surface of the material. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations.

Category	Heterobifunctional PEG
Molecular Weight	Customizable
Storage	-20°C for long-term preservation, keep in dry and avoid sunlight. Avoid repeated freezing and thawing.

Structure of MAL-PEG-Silane, MW 1k-10k

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

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Catalog	Molecular Weight	Availability	actions
BPG-0902-1	MAL-PEG-Silane, MW 1k	In stock	Inquiry
BPG-0902-2	MAL-PEG-Silane, MW 2k	In stock	Inquiry
BPG-0902-3	MAL-PEG-Silane, MW 3.4k	In stock	Inquiry
BPG-0902-4	MAL-PEG-Silane, MW 5k	In stock	Inquiry
BPG-0902-5	MAL-PEG-Silane, MW 10k	In stock	Inquiry

cGMP Capacity

cGMP-compliant manufacturing options
Comprehensive QC testing with COA, MSD
From mg and g to kg-scale production
In-stock supply in the US and Europe
Global supply & fast worldwide delivery
One-stop PEGylation services
Custom PEG reagents synthesis
Click chemistry reagents
Bioconjugation & drug delivery
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Specification
Key Product Attributes
Reaction & Conjugation Properties
References

Solubility

Soluble in water, DMSO and DMF. Freshly prepared before use.

PEGType	Polymeric Functional PEG
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Thiols; Hydroxylated / Silanol Surfaces
ReactionChemistry	Maleimide-Thiol Conjugation; Silanization / Surface Coupling
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides
ResearchUse	Thiol-Selective Biomolecule Conjugation; Surface Silanization / Immobilization; Surface / Nanoparticle Functionalization

1. Ma K, Zhang D, Cong Y, et al. Elucidating the mechanism of silica nanoparticle PEGylation processes using fluorescence correlation spectroscopies.Chemistry of Materials, 2016, 28(5): 1537-1545.
2. Ma K, Wiesner U. Modular and orthogonal post-PEGylation surface modifications by insertion enabling penta-functional ultrasmall organic-silica hybrid nanoparticles.Chemistry of Materials, 2017, 29(16): 6840-6855.