| Category | Maleimide(-MAL) PEG |
| Molecular Weight | Customizable |
MAL-PEG-C1-NHS, MW 1k-4k
Cat No.: BPG-3319
4.5 
Maleimide-PEG-C1-NHS is a heterofunctional PEG derivative with maleimide and NHS ester at both ends of the molecular chain. It is a useful cross-linker with a PEG spacer group. At neutral pH, maleimide can react quickly with sulfhydryl/sulfhydryl groups to form stable sulfide bonds. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen. NHS is a white crystalline substance that can be used as a pharmaceutical intermediate for the production of Semi-synthetic Kanamycin or as a solid-phase synthetic linker for polypeptides. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. MAL-PEG-NHS can be easily incorporated into liposomes and other nanoparticles through the NHS-amine reaction.
Structure of MAL-PEG-C1-NHS, MW 1k-4k
Ordering Information
*For research and manufacturing use only. We do not sell to patients.
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Professional Solutions for Molecular Research
| Catalog | Molecular Weight | Availability | actions |
|---|---|---|---|
| BPG-3319-1 | MAL-PEG-C1-NHS, MW 1k | ||
| BPG-3319-2 | MAL-PEG-C1-NHS, MW 2k | ||
| BPG-3319-3 | MAL-PEG-C1-NHS, MW 3.5k | ||
| BPG-3319-4 | MAL-PEG-C1-NHS, MW 4k |
cGMP Capacity
- cGMP-compliant manufacturing options
- Comprehensive QC testing with COA, MSD
- From mg and g to kg-scale production
- In-stock supply in the US and Europe
- Global supply & fast worldwide delivery
- One-stop PEGylation services
- Custom PEG reagents synthesis
- Click chemistry reagents
- Bioconjugation & drug delivery
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | Maleimide-PEG-C1-NHS |
| PEGType | Polymeric Functional PEG |
| PEGArchitecture | Linear |
| Functionality | Heterobifunctional |
| ReactiveToward | Thiols; Primary Amines |
| ReactionChemistry | Maleimide-Thiol Conjugation; Activated-Ester Amine Coupling |
| BiomoleculeCompatibility | Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides |
| ResearchUse | Amine-Selective Biomolecule Coupling; Thiol-Selective Biomolecule Conjugation |
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MAL-PEG-C1-NHS, MW 1k-4k
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